Short CV
1988 | DEA, University of Paris-XI. |
1991 | Thesis (Ph.D.) University of Paris-XI. |
1998 | « Habilitation Diriger Recherches », University of Paris-XI. Research Experience/ Posts |
1987-1991 | Ph.D. Student. Laboratory of Endocrinology and Cellular Regulations, URA1131, CNRS, Orsay, France. |
1992-1998 | Postdoctoral Research Fellow and Research Associate at INSERM. Gerontology Research Laboratory, U118, Paris. |
1999 | Visiting Researcher. Department of Ophthalmology, Jules Stein Eye Institute, UCLA, Los Angeles. |
2000-2002 | Group Leader and Research Associate at INSERM. Retinal Development, Aging and Pathology Laboratory, U450, INSERM, Paris. |
2003-Present | Group Leader and Research Director at INSERM. Laboratory of Cellular and Molecular Pathophysiology of the Retina, INSERM, Vision Institute, Paris. |
- Central nervous system development.
- Stem cell research.
- Retinal gene transfer.
- Retinal imaging.
- Association for Research in Vision and Ophthalmology (ARVO)
- French society of neurosciences
Research Group
Laboratory of Cellular and Molecular Pathophysiology of the Retina
Analysis of molecular mechanisms involved in retinal progenitor cell differentiation
Key Publications
- Goureau O, Lepoivre M, Becquet F, Courtois Y. (1993).
Differential regulation of inducible NO synthase by bFGF and TGF-beta in bovine retinal pigmented epithelial cells Proc.
Natl. Acad. Sci. USA 90, 4276-4280.
- Goureau O, Bellot J, Thillaye B, Courtois Y, de Kozak Y. (1995)
Increased nitric oxide production in endotoxin-uveitis : reduction of uveitis by an inhibitor of nitric oxide synthase.
J. Immunol. 154, 6518-6523.
- Faure V, Courtois Y, Goureau O. (1997)
Inhibition of inducible NO synthase expression by interferons in bovine retinal pigmented epithelial cells.
J. Biol. Chem. 272, 32169-32175.
- Sennlaub F, Courtois Y and Goureau O. (2001)
Inducible NO synthase inhibits vascularization of the ischemic retina: the switch from retinal to vitreal neovascularization.
J. Clin. Invest. 107, 717-725.
- Sennlaub F, Courtois Y, Goureau O. (2002)
Inducible NO synthase mediates retinal apoptosis in a murine model of ischemic proliferative retinopathy.
J. Neurosci. 22, 3987-3993
- Rhee DK, Goureau O, Chen S, Yang XJ. (2004)
Cytokine-induced Signal Transducer and Activator of Transcription 3 (STAT3) activation in photoreceptors precursors regulates rod differentiation in the developing mouse retina.
J. Neurosci. 24, 9779-9788.
- Roger J, Brajeul V, Thomasseau S, Hienola A, Sahel JA, Guillonneau X, Goureau O. (2006)
Involvement of Pleiotrophin in CNTF-mediated differentiation of the late retinal progenitor cells.
Dev Biol. 298: 527-539
Research Groups
People