Short CV
2011- | Professor of Retinal Studies, UCL Institute of Ophthalmology |
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2007- | Faculty Investigator, National Institute for Health Research |
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2007- | Diabetes Theme Leader, NIHR Biomedical Research Centre |
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2005-10 | Wellcome Advanced Fellow, UCL Institute of Ophthalmology |
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2004-5 | Clinical Fellow in Vitreoretinal Surgery, Moorfields Eye Hospital |
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2003-4 | Specialist Registrar in Ophthalmology, Moorfields Eye Hospital |
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1989-92 | St. Mary's Hospital Medical School, London |
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1986-89 | King's College, Cambridge |
- Association for Research in Vision and Ophthalmology (ARVO)
- Royal College of Ophthalmologists
- European Society of Ophthalmology
James Bainbridge |
Research Group
Molecular Therapy Research
Key Publications
- Bainbridge JW, Smith AJ, Barker SS, Robbie S, Henderson R, Balaggan K, Viswanathan A, Holder GE, Stockman A, Tyler N, Petersen-Jones S, Bhattacharya SS, Thrasher AJ, Fitzke FW, Carter BJ, Rubin GS, Moore AT, Ali RR.
Effect of Gene Therapy on Visual Function in Leber's Congenital Amaurosis.
N Engl J Med. 2008 358:2231–2239 - Mowat F, Luhmann U, Duran Y, Smith AJ, Harten S, Shukla D, Maxwell PH, Ali R and Bainbridge JWB.
HIF-1alpha and HIF-2alpha are differentially activated in distinct cell populations in retinal ischaemia.
PLoS ONE. 2010; 5(6);e11103 - C Lange, P Stavrakas, UFO Luhmann, J da Silva, RR Ali, Z Gregor, J Bainbridge
Intraocular oxygen distribution in advanced proliferative diabetic retinopathy.
Am J Opththalmol. In press - F Mowat, S Petersen-Jones, H Williamson, D Williams, P Luthert, R Ali and J Bainbridge.
Detailed topographical characterisation of cone photoreceptors and the area centralis of the canine retina.
Mol Vision 2008 2008;12:2518-27 - da Silva J, Kwan A, Bunce C and Bainbridge JWB.
Predicting visual outcome following retinectomy for retinal detachment,
Brit J Ophthal 2008 92 (7) 954-8 - JWB Bainbridge, A Mistry, FC Schlichtenbrede, A Smith, C Broderick, M De Alwis, A Georgiadis, PM Taylor, M Squires, C Sethi, D Charteris, AJ Thrasher, D Sargan and RR Ali.
Stable rAAV-mediated transduction of rod and cone photoreceptors in the canine retina.
Gene Therapy 2003; 10: 1336-44 - JWB Bainbridge, A Mistry, K Binley, M De Alwis, A Thrasher, S Naylor, R Ali.
Hypoxia-regulated transgene expression in experimental retinal and choroidal neovascularisation
Gene Therapy 2003; 10(12): 1049-54 - JWB Bainbridge, H Jia, D Selwood, RR Ali, and I Zachary.
Peptides Encoded by exon 6 of VEGF inhibit VEGF-induced angiogenesis in vitro and ischaemic retinal neovascularisation in vivo.
Biochem Biophys Res Commun 2003; 302(4):793-9 - JWB Bainbridge, A Mistry, M De Alwis, E Paleog, A Baker, AJ Thrasher and RR Ali.
Inhibition of retinal neovascularisation by gene transfer of soluble VEGF receptor sFlt-1.
Gene Therapy 2002;9: 320-326 - JWB Bainbridge, C Stephens, K Fowler, C Demaison, A Halfyard, AJ Thrasher and RR Ali.
In-vivo gene transfer to the mouse eye using an HIV-based lentiviral vector: efficient long-term transduction of corneal endothelium and retinal pigment epithelium.
Gene Therapy 2001;8:1665-1668.
Research Groups
People