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Alan Wright


Short CV

  • Batchelor of Medicine/Surgery University of St Andrews
  • PhD (Genetics) University of Edinburgh
  • Scientific Staff MRC Human Genetics Unit since 1981

Scientifc Interest

  • Cell death mechanisms in retinal degeneration
  • Disease mechanisms in RPGR and C1QTNF5 retinal degenerations

Key Publications

  1. Shu X, Zeng Z, Eckmiller MS, Gautier P, Vlachantoni D, Manson FD, Tulloch B, Sharpe C, Gorecki DC, Wright AF (2006)
    Developmental and tissue expression of Xenopus laevis RPGR.
    Invest Ophthalmol Vis Sci 47, 348-56
  2. Yates JR, Sepp T, Matharu BK, Khan JC, Thurlby DA, Shahid H, Clayton DG, Hayward C, Morgan J, Wright AF, Armbrecht AM, Dhillon B, Deary IJ, Redmond E, Bird AC, Moore AT;
    Genetic Factors in AMD Study Group (2007) Complement C3 variant and the risk of age-related macular degeneration.
    N Engl J Med 357, 553-61.
  3. Campbell H, Carothers AD, Rudan I, Hayward C, Biloglav Z, Barac L, Pericic M, Janicijevic B, Smolej-Narancic N, Polasek O, Kolcic I, Weber JL, Hastie ND, Rudan P, Wright AF (2007)
    Effects of genome-wide heterozygosity on a range of biomedically relevant human quantitative traits.
    Hum Mol Genet 16, 233-41.
  4. Shu X, Black GC, Rice JM, Hart-Holden N, Jones A, O'Grady A, Ramsden S, Wright AF (2007)
    RPGR mutation analysis and disease: an update.
    Hum Mutat 28, 322-8.
  5. Vitart V, Rudan I, Hayward C, Floyd J, Gray, NK, Palmer CNA, Knott SA, Kolcic I, Polasek O, Graessler J, Wilson JF, Marinaki A, Riches PL, Janicijevic B, Smolej-Narancic N, Gorgoni B, Morgan J, Campbell S, Biloglav Z, Barac-Lauc L, Pericic M, Martinovic Klaric I, Zgaga L, Hohenstein P, Wild SH, Shu X, Kimber CH, Richardson WA, Tenesa A, Fairbanks LD, Aringer M, McKeigue PM, Ralston S, Morris AD, Rudan P, Hastie ND, Campbell H, Wright AF.
    The major facilitator superfamily member SLC2A9 is a novel uric acid transporter influencing serum urate concentrations, urate excretion and gout.
    Nat Genet 40, 437-42.
Alan Wright
Alan Wright

Research Group

MRC Human Genetics Unit

Molecular Genetics of Human Retinal Degeneration

Contact

MRC Human Genetics Unit

Crewe Road
Edinburgh EH4 2XU
United Kingdom

Phone: 00-131-467-8437
Fax: 00-131-467-8456

Email: alan.wright[at]hgu.mrc.ac.uk
Website: www.hgu.mrc.ac.uk

Research Groups

People