Short CV
‘Principal Investigator’:
2003-present, UNIVERSITY COLLEGE DUBLIN: College Lecturer in School of Biomolecular & Biomedical Sciences, Career-track Investigator, Conway Institute,
‘Postdoctoral Fellow’:
2000-2003, UNIVERSITY OF WASHINGTON, SEATTLE, USA: Senior fellow in Prof. James Hurley’s lab. Projects analysed eye development using mutant zebrafish and investigated cone photoreceptor function using transgenic zebrafish.
1999-2000, UNIVERSITY OF NOTRE DAME, INDIANA, USA: Postdoctoral fellow in Prof. David Hyde’s lab. Projects include characterization of promoters directing rod photoreceptor-specific expression in transgenic zebrafish.
‘Graduate Student’
1994-1998, W. ALTON JONES CELL SCIENCE CENTER, NEW YORK, USA: Ph.D. thesis research under supervision of Dr. John Crabb. Studies investigated the regulation of CRALBP transcription, targeted disruption of the mouse CRALBP gene, and identification and analysis of a mutation in CRALBP segregating with retinitis pigmentosa.
- Retinal/macular degeneration
- Gene regulatory networks in the eye
- Ocular angiogenesis / neovascularisation
- Drug Discovery and Development
- Association for Research in Vision and Ophthalmology (ARVO)
- ISOCB
Breandan Kennedy |
Key Publications
- 2010, ML. Cederlund, T Baden, V Vendrell, L Lagnado, VP Connaughton and BN. Kennedy.
Zebrafish Tg(7.2mab21l2:EGFP) Transgenics Reveal A Unique Population Of Retinal Amacrine Cells.
in press. - 2010, J Yin, S McLoughlin, IB Jeffery, A Glaviano, BN Kennedy, DG Higgins
Integrating multiple genome annotation databases improves the interpretation of microarray gene expression data. BMC GENOMICS.
Jan 20;11(1):50. PMID: 20089164. - 2010, Alvarez Y, Chen K, Reynolds A, Waghorne N, O'Connor J. and. Kennedy. BN.
Predominant Cone Photoreceptor Dysfunction in a Hyperglycaemic Model of Non- Proliferative Diabetic Retinopathy.
Dis Model Mech. Mar-Apr;3(3-4):236-45 PMID: 20142328 - 2009, Y. Alvarez, O Astudillo-Fernandez, L. Jensen, A. Reynolds, N. Waghorne, D. Brazil, Y. Cao, J. O'Connor, BN Kennedy.
Selective Inhibition of Retinal Angiogenesis by Targeting PI3 Kinase". Plos One.
Nov 17;4(11):e7867.PMID: 19924235. - 2009, Malicki, J and Kennedy B.N,
What drives cell morphogenesis - a look inside the vertebrate photoreceptor.
Dev. Dyn. Sep;238(9):2115-38. Review. PMID: 19582864 - 2008, Collery R, McLoughlin S, Vendrell V, Finnegan J, Crabb JW, Saari JC, Kennedy BN.
Duplication And Divergence Of Zebrafish CRALBP Genes Uncovers A Novel Role For RPE- And Muller-CRALBP In Cone Vision.
Invest Ophthalmol Vis Sci. Sep;49(9):3812-20. PMID: 18502992 - 2008; Smyth VA, Di Lorenzo D, Kennedy BN.
A novel, evolutionary conserved enhancer of cone photoreceptor-specific expression.
J Biol Chem. 18;283(16):10881-91; [Epub ahead of print] - 2007, Alvarez, Y.; Cederlund, M. L.; Cottell, D. C.; Bill, B. R.; Ekker, S. C.; Torres-Vazquez, J.; Weinstein, B. M.; Hyde, D. R.; Vihtelic, T. S.; Kennedy, B. N.
Genetic determinants of hyaloid and retinal vasculature in zebrafish.
BMC Dev Biol. 7, 114. - 2007, Kennedy, B.N.; Yolanda Alvarez; Brockerhoff, S.E.; Stearns, G.; Sapetto-Rebow, B., Taylor, M.R.; and Hurley, J.B.
Identification Of A Zebrafish Cone-Specific Promoter And Genetic Rescue Of Achromatopsia In The nof Mutant.
Invest. Ophth. Vis. Sci., 48, 522-529. - 2004, Kennedy, B.N., Stearns, G.W., Smyth, V.S., Ramamurthy, V, Ankoudinova, I., Van Eeden, F, Raible, D., Hurley, J.B. and Brockerhoff, S.E.
Zebrafish rx3 and mab21I2 Are Required During Eye Morphogenesis.
Dev. Biol. 270, 2, 336-342.
Research Groups
People