Short CV
Since 2009 | Dean, Faculty of Chemistry and Pharmacy, LMU München |
2007-2009 | ViceDean, Faculty of Chemistry and Pharmacy, LMU München |
1999 | Professor (C4) and Chair of Pharmacology, Department of Pharmacy, LMU München |
1991-1999 | Research Assistant, Institute of Pharmacology and Toxicology, TU München |
1990 | Dr. rer.nat. , Saarland University |
1988-1990 | Research Assistant, Institute of Physiological Chemistry, Saarland University |
1983-1998 | Study of Pharmacy, Saarland University |
Scientifc Interest
- Ion channel function in retinal circuits
- Hyperpolarization-activated cation channels (HCN channels)
- Genetic mouse models
- Molecular basis of photoreceptor degeneration
- Therapeutic rescue of retinal proteins via viral gene transfer
Martin Biel |
Research Group
Pharmacology
Key Publications
- Griessmeier K, Cuny H, Rötzer K, Griesbeck O, Harz H, Biel M#, Wahl-Schott C.# (2009)
Calmodulin is a functional regulator of Cav1.4 L-type Ca2+ channels.
J.Biol.Chem. 284:29809-29816 - Michalakis S, Reisert S, Geiger H, Wetzel C, Zong X, Bradley J, Spehr M, Hüttl S, Gerstner A, Pfeifer A, Hatt H, Yau KW, and Biel M (2006)
Loss of CNGB1 protein leads to olfactory dysfunction and subciliary CNG channel trapping.
J. Biol. Chem. 281:35156-35166 - Wahl-Schott C, Baumann L, Cuny H, Eckert C, Griessmeier K, Biel M (2006)
Switching off calcium-dependent inactivation in L-type calcium channels by an autoinhibitory domain.
Proc. Acad. Sci. USA. 103:15657-15662 - Hüttl S, Michalakis S, Seeliger S, Luo D, Acar N, Geiger H, Hudl K, Mader R, Haverkamp S, Moser M, Pfeifer A, Gerstner A, Yau KW, Biel M (2005)
Impaired channel targeting and retinal degeneration in mice lacking the cyclic nucleotide-gated channel subunit CNGB1
J. Neurosci. 25:130-138 - Hattar S, Lucas RJ, Mrosovsky N, Thompson S, Douglas RH. Hankins MW, Lem J, Biel M , Hofmann F, Foster RG, Yau KW (2003)
Melanopsin and rod-cone photoreceptive systems account for all major accessory visual functions in mice.
Nature 424:75-81 - Ludwig A, Budde T, Stieber J, Moosmang S, Wahl C, Holthoff K, Langebartels A, Wotjak C, Munsch T, Zong X, Feil S, Feil R, Lancel M, Chien KR, Konnerth A, Pape HC, Biel M, Hofmann F. (2003)
Absence epilepsy and sinus dysrhythmia in mice lacking the pacemaker channel HCN2.
EMBO J 15:216-224 - Seeliger M, Grimm C, Stahlberg F, Friedburg C, Jaissle G, Zrenner E, Guo H, Remé C, Humphries P, Hofmann F, Biel M, Fariss RN, Redmond TM, Wenzel A (2001)
New views on RPE65 deficiency: The rod system is the source of vision in a mouse model of Lebers congenital amaurosis.
Nature Genet 29:70-74 - Gerstner A, Zong X, Hofmann F, Biel M (2000)
Molecular cloning and functional characterization of a new modulatory CNG channel subunit from mouse retina.
J Neurosci 20:1324-1332 - Biel M, Seeliger M, Pfeifer A, Kohler K, Gerstner A, Ludwig A, Jaissle G, Fauser S, Zrenner E, Hofmann F. (1999)
Selective loss of cone function in mice lacking the cyclic nucleotide-gated channel CNG3.
Proc Natl Acad Sci USA 96:7553-7557 - Ludwig A, Zong X, Jeglitsch M, Hofmann F, Biel M (1998)
A family of hyperpolarization-activated mammalian cation channels.
Nature 393:587-591
Research Groups
People