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Agenda of the Young Researcher Vision Camp 2010

Final version, 2010-06-21

Friday, June 25th, 2010

until 16:30 Arrival
18:00-19:00 Keynote Lecture I
"Stem Cell Research: Myth And Reality"
Dr Dusko Ilic MD PhD
Senior Lecturer in Stem Cell Science, School of Biomedical and Health Sciences, Wing Guy's Hospital Great Maze Pond London, UKSenior Lecturer in Stem Cell Science, School of Biomedical and Health Sciences, Wing Guy's Hospital Great Maze Pond London, UK
19:30-open end Open-air Barbecue (campfire outside the castle)
courtesy supported by EVER – www.ever.be

Saturday, June 26th, 2010

06:00-07:00 Early morning exercises
07:00 Breakfast
08:00-09:00

SESSION I: 'Function and Exploitation of Retinal microRNAs'
CHAIR: Arpad Palfi, Dublin, Ireland

  • "Data mining of miRNA expression from retinal gene expression microarray"
    Jun Yin, Bioinformatics Laboratory, Conway Institute, University College Dublin, Ireland
  • "MicroRNAs couple cell fate and developmental timing in retinal histogenesis"
    Sarah Decembrini, Developmental Biology Unit, Institute of Child Health, University College London, UK
  • "Regulation of microRNA expression in an in vitro model of retinal cell differentiation"
    Laura Harwood, Centre for Vision Science, Queen’s University Belfast, UK
  • "Exploitation of microRNA-based gene repression in Rhodopsin-linked retinitis pigmentosa"
    Claire Kilty, Smurfit Institute of Genetics, Trinity College Dublin, Ireland
09:00-10:00

SESSION II: ‘Proteomics in Vision Research’
CHAIR: Stefanie Hauck, Munich, Germany

  • "Application of LC-MS for microRNA Target Identification in Retinal Degeneration"
    Carol Loscher, Trinitiy College, Dublin, Ireland
  • "Dissecting the connecting cilium protein complex"
    Karlien Coene, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
  • "Differential protein expression in vitreous of autoimmune uveitis"
    Florian Hofmaier, Ludwig Maximilians University, Munich, Germany
  • "Identification of interaction networks relevant for retinal degeneration"
    Matteo Gorza, Helmholtz Zentrum München, Neuherberg, Germany
10:00-10:30 Coffee Break
10:30-11:30

SESSION III ‘Clinical Trials in Vision Research’
CHAIR: Monika Fleckenstein, Bonn, Germany

  • "FAM-Study - a prospective longitudinal natural history study in AMD"
    Arno P. Göbel, University of Bonn, Germany
  • "Improving Outreach Screening for Cataract in India"
    David Kupitz, University of Bonn, Germany
  • Vision mediated by a subretinal electronic implant”
    Katarina Stingl, Department of Ophthalmology Tuebingen, Germany
  • “Clinical Trials - Anything we should care about?”
    Robert P. Finger, University of Bonn, Germany
11:30-12:30

SESSION IV 'Gene Therapy for Retinal Disease'
CHAIR: Sophia Millington-Ward, Dublin

  • Evaluation of rAAV vectors for gene replacement therapy in a new canine model of Leber congenital amaurosis: the RPGRIP1 deficient dachshund dog”
    Elsa Lheriteau, Nantes, France
  • “Protection of photoreceptor cells in a mouse model of RP10”
    Lawrence Tam, Smurfit Institute of Genetics, Trinity College Dublin, Ireland
  • “Retinal Gene Therapy”
    Stylianos Michalakis, University of Munich, Germany
  • “Inhibition of light induced photoreceptor apoptosis by AAV-mediated modulation of the inner blood retina barrier and systemic injection of calpain inhibitors”
    Anh Thi Hong Nguyen, Smurfit Institute of Genetics, Trinity College Dublin, Ireland
12:30-14:00 Lunch
14:00-15:00

SESSION V: ‘Nonmammalian Vision’
CHAIR: Edda Kastenhuber, Zuerich, Switzerland

  • "Expressional and Functional Analysis of mGluR6 in the Zebrafish Retina"
    Marion Haug, University of Zurich, Institute for Molecular Life Sciences, Zurich, Switzerland
  • "Touchdown: Visual Input Orchestrating Landings in Insects"
    Torill Kornfeldt, Lund University, Department of Cell and Organism Biology, Zoology, Lund, Sweden
  • "Processing of Polarization Information in the Central Complex of the Locust Brain"
    Miklós Bech, Philipps University of Marburg, Department of Biology - Neurobiology/Ethology, Marburg, Germany
  • "Visual Behavior of Adult Zebrafish"
    Kaspar Müller, University of Zurich, Institute for Molecular Life Sciences, Zurich, Switzerland
15:10-15:40

Roundtable discussion I
Career opportunities - Academia versus Industry

  • Arnd Carrette
    Pharm-Allergan GmbH
  • Marius Ueffing
    Department for Ophthalmology, Tuebingen Germany
15:50-16:20

Roundtable discussion II
Research – Family - Career

  • Anneke den Hollander
    Radboud University Nijmegen Medical Centre, Department of Ophthalmology, The Netherlands
16:20-16:50 Coffee Break
16:50-17:20

Roundtable discussion III
Career Development and Transferable Skills

  • T. Wheeler-Schilling, S. Diether, M. Bitzer
    Research Management Unit, Department for Ophthalmology, University Hospital Tuebingen
17:30-18:00

Roundtable discussion IV
Postdoc time abroad – where to go?

  • Per Ekstroem
    Lund University, Lund, Sweden
18:15-19:00 Keynote Lecture II
"Vision of Innovation in Ophthalmologic Development"

Prof. Craig Smith, MD
CSU Forum Chair
Clinical Science Unit Head Ophthalmology
Novartis Pharma AG
19:00-19:10 Group Photo
19:15-open end Poster Session
20:30-open end Music, dancing and buffet in the inner bailey

Sunday, June 27th, 2010

07:00-08:00 Early morning exercises
08:00 Breakfast
09:00-10:00

SESSION VI ‘Cell Death Mechanisms in Inherited Retinal Degeneration’
CHAIR: Francois Paquet-Durand, Tuebingen, Germany

  • "The Role of PARP in Photoreceptor Cell Death"
    Ayse Sahaboglu, Institute of Ophthalmic Research, Tuebingen, Germany
  • "Epigenetic Markers in Retinal Degeneration"
    Pietro Farinelli, Lund University, Sweden
  • "Identification of Müller Glia derived Neuroprotective compounds"
    Patricia del Rio Medina, Helmholtz Zentrum Munich, Neuherberg, Germany
  • "Oxidative stress and cell death in two models of retinal pathologies"
    Violeta Sánchez Vallejo, University of Valencia, Spain
10:00-11:00

SESSION VII: ‘Genes and mechanisms involved in myopia development’
CHAIR: Marita Feldkämper, Tuebingen, Germany

  • "The role of genetics in susceptibility to environmentally induced myopia"
    Paul Chen, Cardiff, UK
  • "Contrast adaptation and myopia"
    Arne Ohlendorf, Tuebingen, Germany
  • "Eye shapes as result of various types of imposed defocus"
    Tudor Tepelus, Tuebingen, Germany
  • "Hormones in myopia development"
    Alexandra Marcha Penha, Tuebingen, Germany
11:00-12:00

SESSION VIII: 'Axon glial interactions in the optic nerve'
CHAIR: Virginia Bay, Portsmouth, UK

  • "NMDA receptors and injury in the optic nerve"
    Tahani Huria, Cell Physiology and Pharmacology, University of Leicester, UK
  • "GSK3ß signalling and glial differentiation in the optic nerve"
    Andrea Rivera, Institute of Biomolecular and Biomedical Science, University of Portsmouth
  • "Consequences of impaired oligodendrocyte differentiation for optic nerve function."
    Aiman Saab, Max Planck Institute of Experimental Medicine, Goettingen, Germany
  • “Can MRI distinguish between inflammatory and non-inflammatory demyelinating lesions along the optic nerve of a mouse model of Pelizaeus-Merzbacher disease? A comparison of histological measures and MRI data”
    Fredrik Gruenenfelder, Institute of Comparative Medicine, University of Glasgow, UK
12:00-13:00

SESSION IX: ‘Genetics of Eye Diseases’
CHAIR: Kinga Bujakowska, London, UK

  • “Genotypes and phenotypes of the DB/FOAR syndrome”
    Tina Storm, Anatomisk Institut, Århus Universitet, Denmark
  • “IQCB1 mutations in patients with Leber congenital amaurosis”
    Alejandro Estrada, Nijmegen Centre for Molecular Life Sciences
  • “Novel nonsense, frameshift and splice site mutations in patients with age-related maculopathy”
    John van de Ven, Nijmegen Centre for Molecular Life Sciences
  • “Alterations of the 5’untranslated leader region of SLC16A12 are associated with development of age-related cataract in a female patient.”
    Jurian Zürcher, Institute of Medical Genetics University of Zuerich, Switzerland
13:00-14:30 FAREWELL Lunch