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Mike O. Karl

Short CV

born 1976
1996-2004 MD, Univ. Hamburg, Germany
1999-2002 Doctoral Thesis, Univ. Hamburg, Germany
2002-2004 Junior Research Fellow, Univ. of Pennsylvania, Philadelphia, USA
2004-2005 Research Assistant, Univ. Hamburg, Germany
2006 Kaj Ulrik Linderström-Lang – Award – Freundes- & Förderkreis UKE e.V., Germany
2005-2009 Postdoctoral Work with Thomas A. Reh, University of Washington, Seattle, USA
2009 Innovative Ophthalmology Research Award ARVO-AFER
since 2010 Group Leader CRTD


CV of Mike O. Karl [pdf]

Scientifc Interest

  • Retinal development
  • Retinal regeneration
  • Retinal repair
  • Retinal remodelling
  • Neuroprotection


  • Society for Neuroscience (SfN),
  • German Physiological Society (DPG),
  • Society of General Physiologists (SGP),
  • Society for Developmental Biology (SDB),
  • Association for Research in Vision & Ophthalmology (ARVO)
Mike O. Karl
Mike O. Karl

Research Group


[more information]


Center for Regenerative Therapies Dresden (CRTD)

DFG Research Center and Cluster of Excellence

MTZ TU Dresden
Fetscherstrasse 74

01307 Dresden

Phone: +49-351-458-6103



Key Publications

  1. Karl M.O., Hayes S, Nelson B.R., Tan K., Buckingham B. and Reh T.A.(2008)
    Stimulation of neural regeneration in the mouse.
    Proc Natl Acad Sci U S A. 105(49):19508-13.
  2. Lamba D., Hayes S, Karl M.O. and Reh T.A. (2008)
    BAF60c is a component of the neural progenitor specific BAFcomplex in developing retina.
    Dev Dyn. 237(10):3016-23
  3. Lamba D., Karl M.O. and Reh T.A. (2008)
    Neuronal Regeneration and Replacement: A view from the Eye.
    Cell Stem Cell 2: 538-549.
  4. Lamba D., Karl M.O. and T. Reh (2006).
    Efficient generation of retinal progenitor cells from human embryonic stem cells.
    Proc Natl Acad Sci U S A.. 22;103(34):12769-74.
  5. Karl, M.O., W. Kroeger, S. Wimmers, V. Milenkovic, M. Valtink, K. Engelmann and O. Strauss.
    Endogenous Gas6 and Ca2+-Channel Activation Modulate Phagocytosis by RPE.
    Cell Signal 20 (2008) 1159-1168.
  6. Wimmers, S., Karl M.O. and Strauss O. (2006).
    Ion channels in the Retinal Pigment Epithelium. (Review).
    Prog Retin Eye Res. 2007 May;26(3):263-301.
  7. Karl, M.O., J. C. Fleischhauer, W. D. Stamer, K. Peterson-Yantorno, C. H. Mitchell, R. A. Stone and M. M. Civan (2005).
    Differential P1-Purinergic Modulation of Human Schlemm's Canal Inner-Wall Cells.
    Am J Physiol Cell Physiol 288:784-794.

For complete list of publications:
PubMed-Search for Mike O. Karl

Research Groups