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Liverpool Ocular Oncology Research Group (LOORG)

The Liverpool Ocular Oncology Research Group’s (LOORG’s) mission is to conduct high quality basic, translational and clinical research into the pathogenesis and treatment of adult ocular tumours that will improve patient care and survival. The Liverpool Ocular Oncology Research Group (LOORG) was established by Professor Sarah Coupland and Professor Bertil Damato in 2006. Prof. Coupland has since lead the basic science and translational research portfolio, in addition to being a Consultant Pathologist at the Royal Liverpool University Hospital.

A major strength of the LOORG is the close collaboration between ocular oncology clinicians (Lead, Professor Heimann), pathologists and basic scientists (Dr Sarah Lake and Dr Helen Kalirai) which ensures that the research we conduct addresses the key questions that will bring about improved survival and quality of life for ocular oncology patients.

Group Leader

Sarah E. Coupland
[more information]


University of Liverpool

Molecular and Clinical Cancer Medicine
Institute of Translational Medicine
6th Floor, Duncan Building
L69 3GA Liverpool
United Kingdom

Phone: +44(0)151 706 4494
Fax: +44(0)151 706 5826



Current Research Projects

  • Project 1:
    Identification of regulators of metastasis in uveal melanoma
  • Project 2:
    Proteomic discovery of serum biomarkers in metastatic uveal melanoma
  • Project 3:
    Estimating survival prognosis after treatment of choroidal melanoma
  • Project 4:
    Gross chromosomal abnormalities in iris melanoma
  • Project 5:
    Molecular characteristics of metastatic liver lesions in uveal melanoma: the search for therapeutic targets

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