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Diana Pauly

Short CV

since 10/2014

Group Leader “Immune therapy for degenerative eye diseases”, Department of Ophthalmology, University Hospital Regensburg (Regensburg, Germany)

10/2012 – 09/2014

Group Leader “Immune therapy for degenerative eye diseases”, Institute of Human Genetics , University Regensburg (Regensburg, Germany)

07/2008 – 09/2012

Postdoctoral Fellow, Robert Koch-Institute, Centre for biological threats and special pathogens


PhD degree, Robert Koch-Institute, Centre for biological threats and special pathogens (Berlin, Germany)


CV of Diana Pauly [pdf]

Research Group

Experimental Ophthalmology

[more information]


University Hospital Regensburg

Franz-Josef Strauss Allee 11
93053 Regensburg

Phone: +49 (0) 941 944 9228



Scientifc Interest

Since 2012 Dr. Pauly focuses on complement regulation in the murine and human retina in her own group. One of her main research goals is to elucidate the role of the complement system in age-related macular degeneration (AMD), the leading cause of blindness in the western world. Her projects provide unique and comprehensive insights into the functional role of the non-blood derived, local complement system in the retina and retinal degeneration.


  • ARVO
  • DOG
  • ProRetina
  • and others

Selected Publications

  1. Schäfer N, Grosche A, Schmitt S, Braunger BM, Pauly D. 2017 Complement components showed a time-dependent local expression pattern in constant and acute white light induced photoreceptor damage. Front Mol Neurosci. 10:197. doi: 10.3389/fnmol.2017.00197. eCollection 2017, IF 5.076
  2. Schäfer N, Grosche A, Reinders J, Hauck SM, Pouw RB, Kuijpers TW, Wouters D, Ehrenstein B, Enzmann V, Zipfel PF, Skerka C, Pauly D Complement Regulator FHR-3 Is Elevated either Locally or Systemically in a Selection of Autoimmune Diseases. Front. Immunol. 2016 7:542. doi: 10.3389/fimmu.2016.00542 IF 6.429
  3. Pauly D, Nagel BM, Reinders J, Killian T, Wulf M, Ackermann S, Ehrenstein B, Zipfel PF, Skerka C, Weber BHF A Novel Antibody against Human Properdin Inhibits the Alternative Complement System and Specifically Detects Properdin from Blood Samples, PLoS ONE 2014 May; 9(5): e96371. ISSN 1932-6203, IF 3.234
  4. Gallenkamp J, Spanier G, Woerle E, Englbrecht M, Kirschfink M, Greslechner R, Braun R, Schaefer N, Bauer R, Pauly D. 2017 A novel multiplex detection array revealed systemic complement activation in oral squamous cell carcinoma. Oncotarget. 9(3):3001-3013. doi: 10.18632/oncotarget.22963, IF 5.168
  5. Pujol-Lereis L*, Schäfer N*, Kuhn L, Rohrer B, Pauly D Interrelation between oxidative stress and complement dysregulation in models of age-related macular degeneration. Adv Exp Med Biol. 2016;854:87-93. doi: 10.1007/978-3-319-17121-0_13. ISSN 0065-2598, IF 1.953

Research Groups