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Anterior segment eye research

Our research group focusses on anterior segment eye diseases, i.e. corneal diseases.

Our group comprises of 10 physicians, 1 PhD student, 1 biologist and 1 technician.
Special focus is on translational research in the context of corneal transplantation and ocular surface.

We have a dedicated clinical trials facility (EVI.CT.SE certified) as well as a dedicated basic sciences lab.


  • Rat models for various anterior segment diseases
  • DNA/RNA detection and quantification
  • FACS
  • Elisa (Array-technology)
  • Immunehistology
  • Fluorescence-Microscopy
  • Statistics
  • Databases

Scientific Cooperations

  • Cooperation 1:
    Eric Spierings, Department of Immunology
    UMC Utrecht, The Netherlands.
  • Cooperation 2:
    Daniel Saban, Shepens, Boston, USA.
  • Cooperation 3:
    Rene Duquesnoy,
    University of Pittsburgh Medical Center, USA.

Group Leader

Thomas Reinhard
[more information]


University Eye Hospital Freiburg

Killianstr. 5
79106 Freiburg

Phone: +49 761 270 4001
Fax: +49 761 270 4063



Current Research Projects

  • Project 1:
    Randomized multicentric clinical trial on HLA matching in corneal transplantation
  • Project 2:
    Eludicating the mechanisms of corneal graft rejection with focus on the baby rat model
  • Project 3:
    Tissue engineering for limbal stem cell replacement including a rat model and cell culturing.
  • Project 4:
    Coordinating networks collecting rare corneal diseasees
  • Project 5:
    Histopathologic research on various corneal spreciment.

Research Groups