You are here: » People » Researcher » Zeitz, Christina

Christina Zeitz

Short CV

2007 – present Group leader position, Department of Genetics, Institut de la Vision, INSERM, Paris, France
2003-2007 Postdoctoral fellow, Institute of Medical Genetics, Division of Medical Molecular Genetics and Gene Diagnostics, University Zurich, Switzerland
1999-2003 PhD student, Department of Human Molecular Genetics, Max-Planck-Institute for Molecular Genetics, Berlin, Germany, Institute of Medical Genetics, Division of Medical Molecular Genetics and Gene Diagnostics, University Zurich, Switzerland, Free University Berlin, Germany


CV of Chrisitna Zeitz [pdf]

Scientifc Interest

  • Phenotype-genotype correlations in patients with different eye diseases
  • Congenital stationary night blindness
  • Signalling from photoreceptors to bipolar cells


  • American Society of Human Genetics (ASHG)
  • Association for Research in Vision and Ophthalmology (ARVO)
  • International Society for Genetic Eye Disease & Retinoblastoma (ISGED)

Further Activities

Ad hoc paper reviewer:

  • Investigative Ophthalmology and Visual Sciences
  • Molecular Vision
  • Human Genetics
  • GeneReviews
Christina Zeitz
Christina Zeitz

Research Group

Department of Genetics

Identification of gene defects leading to non progressive or progressive ocular eye diseases from A(udo)-Z(eitz)

[more information]


Institut de la Vision

Department of Genetics

17, rue Moreau
75012 Paris

Phone: +33 1 53 46 25 40
Fax: +33 1 53 46 26 02



Key Publications

  1. Leroy BP, Budde B, Wittmer M, De Baere E, Berger W, Zeitz C (2008)
    A common NYX mutation in Flemish patients with X-linked CSNB. BJO.
    Published online July 2008.
  2. Zeitz C*, Gross AK*, Leifert D, Kloeckener-Gruissem B, McAlear SD, Lemke J, Neidhardt J, Berger B (2008)
    A novel constitutively active rhodopsin mutation (p.Ala295Val) causes autosomal dominant CSNB.
    Invest. Ophthalmol. Vis. Sci. 49: 4105-4114.
  3. Zeitz C (2007)
    Molecular genetics and protein function involved in nocturnal vision.
    Exp Rev of Ophthalmol. 2: 467-485.
  4. Zeitz C, Forster U, Neidhardt J, Feil S, Kälin S, Leifert D, Flor PJ, Berger W (2007)
    Night blindness associated mutations in the ligand-binding, cysteine-rich and transmembrane domains of the metabotropic glutamate receptor 6 abolish protein trafficking.
    Human Mut, 28: 771-786.
  5. Wycisk KA*, Zeitz C*, Feil S, Wittmer M, Forster U, Neidhardt J, Wissinger B, Zrenner E, Wilke R, Kohl S, Berger W (2006)
    Mutation in the auxiliary calcium channel subunit CACNA2D4 causes a mild form of autosomal recessive cone dystrophy.
    Am J Hum Genet, 79: 973-977.
  6. Bahadori R*, Biehlmaier O*, Zeitz C*, Labhart T, Makhankov YV, Forster U, Gesemann M, Berger W, Neuhauss SCF (2006)
    Nyctalopin is essential for synaptic transmission in the cone dominated zebrafish retina.
    Eur J Neurosci, 24: 1664-1674.
  7. Zeitz C, Kloeckener-Gruisem B, Forster U, Kohl S, Magyar I, Wissinger B, Mátyás G, Borruat F, Schorderet DF, Zrenner E, Munier FL, Berger W (2006)
    Mutations in CABP4, the gene encoding the Ca2+-binding protein 4, cause autosomal recessive night blindness.
    Am J Hum Genet, 79: 657-667.
  8. Zeitz C*, Genderen M*, Neidhardt J, Luhmann UFO, Hoeben F, Forster U, Wycisk K, Mátyás G, Hoyng CB, Riemslag F, Meire F, Cremers FPM, Berger W (2005)
    Mutations in GRM6 cause autosomal recessive congenital stationary night blindness with a distinctive scotopic 15 Hz flicker electroretinogram (ERG).
    Invest Ophthalmol Vis Sci, 46: 4328-4335.
  9. Zeitz C*, Scherthan H*, Freier S, Feil S, Suckow V, Schweiger S, and Berger W (2003)
    Functional characterization of protein motifs of NYX (nyctalopin on chromosome X) in mouse and man.
    Invest Ophthalmol Vis Sci, 44: 4184-4191.
  10. Pusch C*, Zeitz C*, Brandau O*, Pesch K, Achatz H, Feil S, Scharfe C, Maurer J, Jacobi FK, Pinckers A, Andreasson S, Hardcastle AJ, Wissinger B, Berger W, and Meindl A (2000)
    The complete form of X-linked congenital stationary night blindness is caused by mutations in a gene encoding a leucine-rich repeat protein.
    Nature Genet, 26: 324-327.

* These authors contributed equally to this work

Research Groups