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Robert Vignali


CV of Robert Vignali [pdf]

Scientifc Interest

  • Retinal cell fate determination
  • Role of transcription factors Xotx2, Xotx5 and Xbh1 in retinal cell committment.
  • Regulation of transcription of Xotx2, Xvsx1 and Xotx5 by microRNA
  • Neural induction and eye development


  • Society of Developmental Biologists

Further Activities

  • Co-organizer of the German-Italian Xenopus Meeting (with Stefano Piccolo and Tomas Pieler)

Key Publications

  1. Onorati M., Cremisi F., Liu Y., He R.-Q., Barsacchi G., Vignali R. (2007)
    A specific box switches the cell fate determining activity of XOTX2 and XOTX5b in the Xenopus retina.
    Neural Development 2: 12.
  2. Decembrini S., Andreazzoli M., Vignali R., Barsacchi G. (2006)
    Timing the generation of distinct retinal cells by homeobox proteins.
    PLoS Biology 4:e272.
  3. Benini F., Onorati M., Altamura S., Manfioletti G., Vignali R. (2006)
    Identification and developmental expression of Xenopus hmga2b.
    Biochem. Biophys. Res. Comm. 351: 392-397.
  4. Lunardi A., Vignali R. (2006)
    Xenopus Xotx2 and Drosophila otd share similar activities in anterior patterning of the frog embryo.
    Dev. Genes Evol. 216: 511-521.
  5. Poggi L., Vottari T., Barsacchi G., Wittbrodt J., Vignali R. (2004)
    The homeobox gene Xbh1 cooperates with proneural genes to specify ganglion cell fate within the Xenopus neural retina.
    Development 131: 2305-2315.
  6. Viczian A., Vignali R., Zuber M.E., Barsacchi G., Harris W.A. (2003)
    XOtx5b and XOtx2 regulate photoreceptor and bipolar fates in the Xenopus retina.
    Development 130: 1281-1294.
  7. Lupo G., Harris W.A., Barsacchi G., Vignali R. (2002)
    Induction and patterning of the telencephalon in Xenopus laevis.
    Development 129: 5421-5436.
  8. Poggi L., Carl M., Vignali R., Barsacchi G., Wittbrodt J. (2002)
    Expression of a medaka (Oryzias latipes) Bar homologue in the differentiating central nervous system and retina.
    Mech. Dev. 114: 193-196.
  9. Vignali R., Colombetti S., Lupo G., Stachel S., Zhang W., Stachel S., Harland R.M., Barsacchi G., (2000)
    Xotx5b, a new member of the Otx gene family, may be involved in anterior and eye development in Xenopus laevis.
    Mech. Dev. 96: 3-13.
  10. Vignali R., Poggi L., Madeddu F., Barsacchi G. (2000)
    HNF1b is required for mesoderm induction in the Xenopus embryo.
    Development 127: 1455-1465
Robert Vignali
Robert Vignali

Research Group

Cell and Developmental Biology Unit

[more information]


University of Pisa

Dipartimento di Biologia
via Luca Ghini 5
56126 Pisa

Via G. Carducci 13

Phone: 0039-050-2211497
Fax: 0039-050-2211495



Research Groups