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Elke Guenther

Elke Guenther is Head of the Department of Cell Biology at the NMI Natural and Medical Sciences Institute at the University Tübingen and Head of Pharmaservices ath the NMI TT GmbH.

Short CV

1985 Diploma in Biology, Uuniversity Konstanz
1986-89 PhD study at the Max-Planck-Institute for Physiological und Clinical Research, Bad Nauheim, and LMU Munich, Zoological Institute
1990 Postdoc, Max-Planck-Institute for Psychiatry, Dept. Neurophysiology, Martinsried, Germany
1991-2002 Head of the Laboratory for Cell Physiology and Molecular Biology at the Department of Experimental Ophthalmology, University Eye Hospital Tübingen
2004 Appointed Professor, Faculty of Biology, Animal Physiology


CV of Elke Guenther [pdf]

Scientifc Interest

  • Function and dysfunction of ion channels and neurotransmitter receptors
  • Physiology and pathophysiology of intercellular signalling
  • Signal propagation in cellular networks
  • Microelectrode array-based biosensors
  • Development of neuronal circuitries


  • Association for Research in Vision and Ophthalmology (ARVO)
  • Neuroscience Society
  • FENS
  • DZG
Elke Guenther
Elke Guenther

Research Group

Cell Biology

[more information]


University Tuebingen

Natural and Medical Sciences Institute

Markwiesenstrasse 55
72770 Reutlingen

Phone: +49-(0)7121-5153054
Fax: +49-(0)7121-5153016



Key Publications

  1. Metzger M., Bareiss P.M., Danker T., Wagner S., Hennenlotter J., Guenther E., Stenzl A., Koenigsrainer A., Skutella T., Just L. (2009)
    Expansion and differentiation of neural progenitors derived from the human adult enteric nervous system.
    Gastroenterology, 137(6):2063-2073.
  2. Meyer Th., Sartipy P., Blind F., Leisgen Ch., Guenther E. (2007)
    New cell models and assays in cardiac safety profiling.
    Expert Opin. Drug Metab. Toxicol. 3(4):507-517 (2007)
  3. Fries J.E., Goczalik I.M., Wheeler-Schilling, Kohler K., Guenther E., Wolf S., Wiedemann P., Bringmann A., Reichenbach A., Francke A., Pannicke T. (2005)
    Identification of P2Y receptor subtypes in human Müller glial cells by physiology, single cell RT-PCR, and immunohistochemistry.
    Invest. Ophthalmol. Vis. Sci., 46:3000-3007.
  4. Guenther E., Schmid S., Wheeler-Schilling T., Albach G., Gründer T., Fauser S., Kohler K. (2004)
    Developmental plasticity of NMDA receptor function in the retina and the influence of light.
    FASEB J., 18: 1-8.(online: July 9, 10.1096/fj.03-0618fje)
  5. Innocenti B., Pfeiffer S., Zrenner E., Kohler K., Guenther E. (2004)
    ATP-induced cell permeabilization in the inner retina.
    J Neurosci. 24(39):8577-83
  6. Pinzon-Duarte G., Arango-Gonzales B., Kohler K., Guenther E. (2004)
    Effects of brain-derived neurotrophic factor on cell survival, differentiation and patterning of neuronal connections and Muller glia cells in the developing retina.
    Europ. J. Neurosci., 19, 1475-1484.
  7. Schniepp R., Kohler K., Ladewig T., Guenther E., Henke G., Boehmer Ch., Rothstein J.D., Bröer S., Lang F. (2004)
    Serum and glucocorticoid inducible kinase SGK1 colocalizes in the retina with and in vitro stimulates the glutamate transporter EAAT3.
    Invest. Ophthalmol. Vis. Sci., 45:1442-1449.
  8. Hofmann F., Guenther E., Volkmer H., Klink O., Hämmerle H. and Leibrock C. (2004)
    Functional re-establishment of the perforant pathway in organotypic co-cultures on microelectrode arrays.
    Brain Res. 1017(1-2):184-96.
  9. Felmy F., Pannicke T., Richt J.A., Reichenbach A., Guenther E. (2001)
    Electrophysiological properties of rat retinal Müller (glial) cells in postnatally developing and in pathologically altered retinae.
    Glia, 34(3): 190-199.

Research Groups