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Heping Xu

Short CV

1987 MD, Hengyang Medical College, China
1994 PhD, Hunan Medical University, China
1997 Post-doc Research Scientist, Seikagaku Corporation, Japan
2000 Post-doc Research Fellow, University of Aberdeen, UK
2005 RCUK Independent Fellow, University of Aberdeen, UK
2008 Senior RCUK Fellow, University of Aberdeen, UK
2009 Senior Lecturer, Queen’s University Belfast, UK


CV of Heping Xu [pdf]

Scientifc Interest

My research interests focus on the role of the immune response in various retinal diseases including age-related macular degeneration, diabetic retinopathy and retinal angiogenesis.  The goal of my research is to use the  knowledge to develop novel therapy.


  • British Society for Research into Ageing
  • Association for Research in Vision and Ophthalmology (ARVO)
  • British Society for Immunology
  • Overseas Chinese Society of Ophthalmology & Vision Research
Heping Xu
Heping Xu

Research Group

Heping Xu

[more information]


Queen’s University Belfast

Centre for Vision and Vascular Science
Institute of Clinical Science-A

Grovenor Road
BT12 6BA Belfast
Northern Ireland, UK

Phone: 028 906 33615
Fax: 028 906 32699



Key Publications

  1. Chen M, Muckerise E, Forrester JV, Xu H.
    Immune activation in retinal aging: a gene expression study.
    Invest Ophthalmol Vis Sci. 2010. 51(11):5888-5896.
  2. Chen M, Muckersie E, Forrester JV, Xu H.
    Inhibition of the alternative pathway of complement activation reduces inflammation in experimental autoimmune uveoretinitis.
    Eur J Immunol. 2010. 40: 2870-2881
  3. Ganesan PB, He S, Xu H.
    Analysis of retinal circulation using an image-based network model of retinal vasculature.
    Microvasc Res. 2010, 80(1):99-109.
  4. Xu H, Chen M, Forrester JV. (Review)
    Para-inflammation in the aging retina.
    Prog Retin Eye Res. 2009. 28(5):348-368.
  5. Chen M, Muckersie E, Robertson M, Forrester JV, Xu H.
    Up-regulation of complement factor B in retinal pigment epithelial cells is accompanied by complement activation in the aged retina.
    Exp Eye Res. 2008, 87(6):543-440.
  6. Chen M, Muckersie E, Roberston M, Fraczek M, Forrester JV, Xu H.
    Characterization of a mouse retinal pigment epithelial cell line: B6-RPE07.
    Invest Ophthalmol Vis Sci. 2008, 49(8):3699-3706.
  7. Xu H, Chen M, Manivannan A, Lois N, Forrester JV.
    Age-dependent accumulation of lipofuscin in perivascular and subretinal microglia in experimental mice.
    Aging Cell. 2008. 7; 58-68.
  8. Xu H, Dawson R, Forrester JV and Liversidge J.
    Identification of novel dendritic cell populations in mouse retina.
    Invest Ophthalmol Vis. Sci. 2007. 48:1701-10.
  9. Chen M, Forrester JV, Xu H.
    Synthesis of complement factor H in RPE cells is down-regulated by oxidized photoreceptor outer segment.
    Exp Eye Res. 2007. 84: 635-45.
  10. Xu H, Manivannan A, Dawson R, Crane IJ, Mack M, Sharp P and Liversidge J.
    Differentiation to the CCR2+ Inflammatory Phenotype In Vivo Is a Constitutive, Time-Limited Property of Blood Monocytes and Is Independent of Local Inflammatory Mediators.
    J Immunol. 2005. 175:6915-23.

Research Groups