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Jochen Graw

Short CV

1953 Born in Heidelberg, Germany
1979 Diploma in Biochemstry (University of Tübingen/Germany)
1981 PhD in Biology /Molecular Genetics (University of Constance/Germany)
1991 Habilitation for Genetics (Ludwig-Maximilians University of Munich/Germany)
1992 Head of the group “Molecular Eye Development” at the GSF Research Center Neuherberg (now: Helmholtz Center Munich)
1999 apl. Prof. at the Technical University of Munich/Germany
2002–2008 Member of the supervisory board of the GSF Research Center
2010 Member of the Management Commitee of the Helmholtz Center Munich


CV of Jochen Graw [pdf]

Scientifc Interest

Understanding of genetic causes of visual dysfunction in mouse and human, from the cornea to the visual cortex.


  • Association for Research in Vision and Ophthalmology (ARVO)
  • EVER
  • EVI
  • German Genetics Society (Secretary)

Further Activities

  • Member of the Editorial Board: Ophthalmic Research (Section Editor for Biochemistry, Molecular Biology, Molecular Genetics), Experimental Eye Research, The Open Ophthalmology Journal
  • Ad-hoc reviewer for several journals including Developmental Biology, Human Molecular Genetics; Investigative Ophthalmology & Visual Sciences; Mammalian Genome, Molecular Vision, ….
  • Reviewer for scientific organizations: Fight for Sight (UK); German-Israeli Foundation for Scientific Research & Development; Medical Research Council (UK); Wellcome Trust (UK)
Jochen Graw
Jochen Graw

Research Group

Laboratory of Molecular Eye Development


Helmholtz Center Munich

German Research Center for Environmental Health
Institute of Developmental Genetics
Ingolstädter Landstr. 1
85764 Neuherberg

Phone: +49-89/3187-2610
Fax: +49-89/3187-4620



Key Publications

  1. Churchill, A., Graw, J.:
    Clinical and Experimental Advances in Congenital and Paediatric Cataracts.
    Phil. Transact. Royal Soc. Ser. B. 366, 2011, 1234-1249.
  2. Graw, J., Welzl, G., Ahmad, N., Klopp, N., Heier, M., Wulff, A., Heinrich, J., Döring, A., Karrasch, S., Nowak, D., Schulz, H., Rathmann, W., Illig, T., Peters, A., Holle, R., Meisinger, C., Wichmann, H.E.:
    The KORA Eye Study: A Population-Based Study on Eye Diseases in Southern Germany (KORA F4).
    Invest. Ophthalmol. Vis. Sci. 2011,52, 7778-7786.
  3. Puk, O., Ahmad, N., Wagner, S., Hrabé de Angelis, Graw, J.:
    First mutation in the βA2-crystallin encoding gene is associated with small lenses and age-related cataracts.
    Invest. Ophthalmol. Vis. Sci. 52, 2011, 2571-2576.
  4. Puk, O., Ahmad, N., Wagner, S., Hrabé de Angelis, Graw, J.:
    Microphakia and congenital cataract formation in a novel Lim2C51T mutant mouse.
    Mol. Vis. 17, 2011, 1164-1171.
  5. Puk, O., Möller, G., Geerlof, A., Krowiorz, K., Ahmad, N., Wagner, S., Adamski, J., Hrabé de Angelis, M., Graw, J.:
    The pathologic effect of a novel neomorphic Fgf9(Y162C) allele is restricted to decreased vision and retarded lens growth.
    PLoS One. 2011, 6, e23678.
  6. Graw, J.:
    Eye Development.
    Curr. Top. Dev. Biol. 90C, 2010, 343-386.
  7. Rosemann, M., Ivashkevich, A., Favor, J., Dalke, C., Hölter, S.M., Becker, L., Rácz, I., Bolle, I., Klempt, M., Rathkolb, B., Kalaydjiev, S., Adler, T., Aguilar, A., Hans, W., Horsch, M., Rozman, J., Calzada-Wack, J., Kunder, S., Gailus-Durner, V., Fuchs, H., Naton, B., Schulz, H., Beckers, J., Busch, D.H., Burbach, J.P.H., Smidt, M.P., Quintanilla-Martinez; L., Esposito, I., Klopstock, T., Klingenspor, M., Ollert, M., Wolf, E., Wurst, W., Zimmer, A., Hrabé de Angelis, M., Atkinson, M., Heinzmann, U., Graw, J.:
    Microphthalmia, Parkinsonism and enhanced nociception in Pitx3416insG mice.
    Mamm. Genome, 21, 2010, 13-27.
  8. Roshan, M., Vijaya, P.H., Lavanya, R.G., Shama P. K., Santhiya, S.T., Graw, J., Gopinath, P.M., Satyamoorthy, K.:
    A novel human CRYGD mutation in a juvenile autosomal dominant cataract.
    Mol. Vis. 16, 2010, 887-896.
  9. Santhiya, S.T., Kumar, G.S., Sudhakar, P., Gupta, N., Klopp, N., Illig, T., Söker, T., Groth, M., Platzer, M., Gopinath, P.M., Graw, J.
    Molecular analysis of cataract families in India: new mutations in the CRYBB2 and GJA3 genes and rare polymorphisms.
    Mol Vis. 16, 2010, 1837-1847.
  10. Ainsbury, E.A., Bouffler, S.D., Dörr, W., Graw, J., Muirhead, C., Edwards, A.A., Cooper, J.:
    Radiation cataractogenesis – a review of recent studies.
    Rad. Res. 172, 2009, 1-9.
  11. Graw, J.: Crystallins.
    Cataract and beyond.
    Exp. Eye Res. 88, 2009, 173-189.
  12. Graw, J., Schmidt, W., Minogue, P.J., Rodriguez, J., Tong, J.J., Klopp, N., Illig, T., Ebihara, L., Berthoud, V.M., Beyer, E.C.:
    The GJA8 allele encoding CX50I247M is a rare polymorphism, not a cataract-causing mutation.
    Mol. Vis. 14, 2009, 1881-1885.
  13. Puk, O., Dalke, C., Calzada-Wack, J., Ahmad, N., Klaften, M., Wagner, S., Hrabé de Angelis, M., Graw, J.:
    Reduced corneal thickness and enlarged anterior chamber in a novel ColVIIIa2G257D mutant mouse.
    Invest. Ophthalmol. Vis. Sci. 50, 2009, 5653-5661.
  14. Puk, O., Esposito, I., Söker, T., Löster, J., Budde, B., Nürnberg, P., Michel-Soewarto, D., Fuchs, H., Wolf, E., Hrabé de Angelis, M., Graw, J.:
    A new Fgf10 mutation in the mouse leads to atrophy of the Harderian gland and slit-eye phenotype in heterozygotes: A novel model for dry-eye disease?
    Invest. Ophthalmol. Vis. Sci. 50, 2009, 4311-4318

Research Groups