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Lab for Retinal Cell Biology

Research group of Prof. Dr. Christian Grimm in Zurich, Switzerland.

Methodology

  • In vivo mouse models of induced and inherited retinal degeneration
  • Molecular biology
  • Immunfluorescence
  • Light- and electronmikroscopy

Cooperations

Cooperation 1:
Yvan Arsenijevic, University of Lausanne, Switzerland

Cooperation 2:
Mathias Seeliger, University of Tubingen, Germany

Cooperation 3:
John Ash, Yun Le, University of Oklahoma, USA

Current Research Projects

Project 1:
Leukemia inhbitory factor as an endogenous survival factor for photoreceptors

Project 2:
Neuroprotection by hypoxic preconditioning

Project 3:
The pathophysiology of Rpe65-R91W as a mouse model for early onset severe retinal dystrophy (EOSRD)

Project 4:
MicroRNAs and their role in hypoxic regulation of gene expression in the retina

Project 5:
Cytoskeleton signaling and small GTPases in retinal degeneration

Group Leader

Prof. Dr. Christian Grimm

more information

Contact

University of Zurich
Lab for Retinal Cell Biology

Dept. Ophthalmology
Frauenklinikstrasse 24
8091 Zurich
Switzerland

Phone: +41 44 255 3905
Fax: +41 44 255 4385

Email: cgrimm[at]opht.uzh.ch
Website: Lab for Retinal Cell Biology

Research Groups

People

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age-related macular degeneration
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cell survival
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cytokines/chemokines
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degenerations/dystrophies
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gene/expression
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growth factors/growth factor receptors
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hypoxia
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neuroprotection
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retinal degenerations: cell biology
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transcription factors
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Retinal degeneration
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neuroprotection
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Leukemia inhibitory factor
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Erythropoietin
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Preconditioning
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