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Eye Diseases

Research Group of Prof. Dr. Valeria Marigo in Modena, Italy.

Methodology

  • Cell culture of retinal neurospheres and of in vitro differentiated rod-like cells
  • Analysis of mRNA and protein localization by in situ hybridization,
  • immunohistochemistry,
  • western blotting,
  • Real-time PCR
  • Cloning strategies for genetic modifications

Cooperations

Cooperation 1:
Dr. Sandro Banfi, Telethon Institute of Genetics and Medicine, Naples, Italy

Cooperation 2:
Prof. Alberto Auricchio, Telethon Institute of Genetics and Medicine, Naples, Italy

Cooperation 3:
Prof. Per Ekstrom, Lund University, Lund, Sweden

Cooperation 4:
Prof. Shomi Bhattacharya, UCL, London, UK

Current Research Projects

Project 1:
Molecular mechanisms of apoptosis in rd1 and P23H mouse models

Project 2:
Molecular defects caused by mutations in PRPF3 pre-mRNA splicing gene

Project 3:
Ocular albinism type 1: in vitro and in vivo analysis of melanosomal defects caused by the loss of OA1.

Group Leader

Prof. Dr. Valeria Marigo

more information

Contact

University of Modena and Reggio Emilia

Department of Biomedical Sciences
Via G. Campi, 287
41100 Modena
Italy

Phone: +39-059-2055392
Fax: +39-059-2055410

Email: valeria.marigo[at]unimore.it
Website: Valeria Marigo / UNIMO

Research Groups

People

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apoptosis/cell death
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degenerations/dystrophies
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differentiation
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in situ hybridization
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microscopy: light/fluorescence/immunohistochemistry
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photoreceptors
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retinal degenerations: cell biology
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retinal pigment epithelium
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retinitis
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Retinal stem cells
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Rod differentiation in vitro
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Molecular mechanisms of apoptosis
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albinism
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