You are here: vision-research.eu » People » Young Researcher » Griciuc, Ana

Ana Griciuc

Current Research Projects

ER stress and apoptotic cell death in the retina occurs as a consequence of impaired turnover of mutant Rhodopsin via activation of stress-specific JNK and p38 mitogen-activated protein kinases. We proved that the absence of ERAD members significantly diminishes Rhodopsin-induced activation of JNK. We also showed that ERAD is important in the degradation and aggregation of both wild type and mutant Rhodopsin.

Methodology

Within my research project we used Drosophila as genetic tool. We also performed knock-down in mammalian cell lines (RNAi, sh-RNA), WB, SDS-PAGE/2D-Electrophoresis/MALDI-TOF-MS and fluorescence microscopy.

Research Group

Department of Protein Science

Contact

Helmholtz Zentrum München
German Research Center for Environmental Health

Ingolstaedter Landstrasse 1,
Buiding 35 Room 8125
85764 Neuherberg-Munich
Germany

Phone: +49-89 3187 3526
Fax: +49-89 3187 4426

Email:
Ana.griciuc[at]helmholtz-muenchen.de

Website:
www.helmholtz-muenchen.de

Documents

CV of Ana Griciuc [pdf]

Research Groups

People

Related Research Groups

aging: visual performance
Oops, an error occurred! Code: 20191208014624381ccb4e
antioxidants
Oops, an error occurred! Code: 20191208014624e9ab7128
apoptosis/cell death
Oops, an error occurred! Code: 2019120801462442552813
cell survival
Oops, an error occurred! Code: 201912080146242a75eab3
chaperones
Oops, an error occurred! Code: 20191208014624ddc4a96f
growth factors/growth factor receptors
Oops, an error occurred! Code: 2019120801462493c33e95
immunohistochemistry
Oops, an error occurred! Code: 20191208014624561a05e7
mitochondria
Oops, an error occurred! Code: 2019120801462433d3ec01
opsins
Oops, an error occurred! Code: 20191208014624d07dbca1
retinitis pigmentosa
Oops, an error occurred! Code: 20191208014624054f60ab
stress response
Oops, an error occurred! Code: 20191208014624de56cc79