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Myopia Research Laboratory

We are investigating the factors that influence why some people develop high myopia (a high degree of short-sightedness), whilst others do not.
Our primary focus is searching for genetic variants that influence susceptibility to myopia.

The group comprises researchers with expertise in optometry, ophthalmology, genetics, epidemiology and optical design.

Methodology

  • Genetic linkage and association studies
  • Animal models of myopia
  • Genetic epidemiology

Scientific Cooperations

  • Cooperation 1:
    The International High Myopia Genetics Consortium
    (P.I. Dr Terri L. Young [Duke University, USA]).
  • Cooperation 2:
    The MyEuropia Myopia Research Training Network
    (P.I. Prof. Frank Schaeffel [University of Tuebingen, Germany])
  • Cooperation 3:
    Avon Longitudinal Study of Parents and Children (ALSPAC) Vision Group
    (P.I. Dr Cathy Williams [University of Bristol]).
  • Cooperation 4:
    Chicken Genetics and Genomics Group, Roslin Institute
    (P.I. Dr Paul Hocking [University of Edinburgh]).
  • Cooperation 5:
    The Centre for Myopia Research, Hong Kong
    (P.I. Prof. Chi Ho To [Polytechnic University of Hong Kong]).

Group Leader

Jeremy Andrew Guggenheim
[more information]

Contact

Cardiff University
School of Optometry & Vision Sciences

Maindy Road
CF24 4LU
Cardiff
UK

Phone: +44 (0) 29 2087 9048
Fax: +44 (0) 29 2087 4859

Email:
Guggenheim[at]cardiff.ac.uk
Website:
www.cardiff.ac.uk/optom/contactsandpeople/academicstaff/guggenheim-jeremy-dr-overview.html

Current Research Projects

  • Project 1:
    The UK Family Study of Myopia: human high myopia genetics.
  • Project 2:
    Mapping QTL for ocular component dimensions in chickens (with Dr J. Erichsen [Cardiff] and Dr P. Hocking [Roslin]).
  • Project 3:
    Is susceptibility to environmentally-induced myopia in chickens genetically-determined?
  • Project 4:
    Genetic and environmental influences in myopia in the ALSPAC cohort (with Dr C. Williams [Bristol]).
  • Project 5:
    Improved ocular biometry in small eyes (with Dr B. Povazay and Prof. W. Drexler [Cardiff]).

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