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Ophthalmic Physics

We study the functional morphology of the human retina by noninvasive optical techniques. Models for spectral fundus reflectance have been developed, which yield individual estimates of the photoreceptor quality and the density of the different absorber in the eye (lens, macular pigment,visual pigment, melanin). Recent work involves epidemiological studies on the relation between nutrition, macular pigment and age-related eye diseases.

Group Leader

Tos Berendschot
[more information]

Contact

University Eye Clinic Maastricht

PO Box 5800
NL-6202 AZ Maastricht
The Netherlands

Phone: +31 43 387 7345
Fax: +31 43 387 5343

Email:
t.berendschot@maastrichtuniversity.nl.

Current Research Projects

  • Project 1:
    Two year, multicenter, double-masked, randomized trial comparing lutein versus placebo
  • Project 2:
    The effect on visual acuity of three monthly intravitreal injections of Bevacizumab with additional injections when needed compared to monthly intravitreal injections Ranibizumab in patients with exudative age-related macular degeneration.
  • Project 3:
    A multicenter that studies the effects of Temporary Inhibition of the Renin-Angiotensin System on future blood pressure and hypertensive organ damage in young prehypertensive adults.
  • Project 4:
    The influence of daily supplementation of eggs enriched with lutein/zeaxanthin on visual function in subjects with age-related macular degeneration
  • Project 5:
    HYBRiD study (HYpertension and BRain Damage)
    A study on cerebral small-vessel disease

Scientific Cooperations

  • Cooperation 1:
    Dr. Ian Murray, Manchester, United Kingdom
  • Cooperation 2:
    Dr. Hendrik Scholl, Bonn, Germany
  • Cooperation 3:
    Dr. Frank Verbraak, Amsterdam, The Netherlands
  • Cooperation 4:
    Dr. Thomas Theelen, Nijmegen, The Netherlands
  • Cooperation 5:
    Dr. John Nolan, Waterford, Ireland

Research Groups

People

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age-related macular degeneration
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aging
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antioxidants
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apoptosis/cell death
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clinical (human) or epidemiologic studies: health care delivery/economics/manpower
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clinical (human) or epidemiologic studies: natural history
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clinical (human) or epidemiologic studies: outcomes/complications
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clinical (human) or epidemiologic studies: prevalence/incidence
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clinical (human) or epidemiologic studies: risk factor assessment
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clinical (human) or epidemiologic studies: systems/equipment/techniques
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clinical (human) or epidemiologic studies: treatment/prevention assessment/controlled clinical trials
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clinical laboratory testing
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clinical research methodology
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degenerations/dystrophies
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image processing
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imaging/image analysis: clinical
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imaging/image analysis: non-clinical
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imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound)
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macula/fovea
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macular pigment
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nutritional factors
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oxidation/oxidative or free radical damage
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photoreceptors
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photoreceptors: visual performance
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quality of life
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radiation damage: light/UV
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reading
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receptors
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receptors: pharmacology/physiology
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vascular endothelial growth factor
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Macular Pigment
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Lutein / Zeaxanthin
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Stiles-Crawford
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Photoreceptors
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