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Ophthalmic Physics

We study the functional morphology of the human retina by noninvasive optical techniques. Models for spectral fundus reflectance have been developed, which yield individual estimates of the photoreceptor quality and the density of the different absorber in the eye (lens, macular pigment,visual pigment, melanin). Recent work involves epidemiological studies on the relation between nutrition, macular pigment and age-related eye diseases.

Group Leader

Tos Berendschot
[more information]

Contact

University Eye Clinic Maastricht

PO Box 5800
NL-6202 AZ Maastricht
The Netherlands

Phone: +31 43 387 7345
Fax: +31 43 387 5343

Email:
t.berendschot[at]maastrichtuniversity.nl.

Current Research Projects

Project 1:
Two year, multicenter, double-masked, randomized trial comparing lutein versus placebo
Project 2:
The effect on visual acuity of three monthly intravitreal injections of Bevacizumab with additional injections when needed compared to monthly intravitreal injections Ranibizumab in patients with exudative age-related macular degeneration.
Project 3:
A multicenter that studies the effects of Temporary Inhibition of the Renin-Angiotensin System on future blood pressure and hypertensive organ damage in young prehypertensive adults.
Project 4:
The influence of daily supplementation of eggs enriched with lutein/zeaxanthin on visual function in subjects with age-related macular degeneration
Project 5:
HYBRiD study (HYpertension and BRain Damage)
A study on cerebral small-vessel disease

Scientific Cooperations

Cooperation 1:
Dr. Ian Murray, Manchester, United Kingdom
Cooperation 2:
Dr. Hendrik Scholl, Bonn, Germany
Cooperation 3:
Dr. Frank Verbraak, Amsterdam, The Netherlands
Cooperation 4:
Dr. Thomas Theelen, Nijmegen, The Netherlands
Cooperation 5:
Dr. John Nolan, Waterford, Ireland

Research Groups

People

Related Research Groups

age-related macular degeneration: Ader, Marius; AIBILI; Arden, Geoffrey; Audo, Isabelle; Beattie, Renwick; Bergen, Arthur; Berger, Wolfgang; Bird, Alan; Cremers, Frans; den Hollander, Anneke; Dias, Aylvin; Enzmann, Volker; Fighting Blindness; Greenwood, John; Grimm, Christian; Grus, Franz; Hammond, Chris; Hauck, Stefanie; Heiduschka, Peter; Hicks, David; Holz, Frank G.; Humphries, Peter; Inglehearn, Chris; Joachim, Stephanie; Johnsen-Soriano, Siv; Julien, Sylvie; Kennedy, Breandan; Larsen, Michael; Lengyel, Imre; Lotery, Andrew John; Moore, Tony; Navea, Amparo; Pastor, Jose-Carlos; Petersen, Michael; Research Group of Tunde Peto; Sennlaub, Florian; Tsilimbaris, Miltiadis; Riva, Charles; Rubin, Gary; Schmetterer, Leopold; Strauss, Olaf; Sørensen, Torben Lykke; Topouzis, Fotis; Ueffing, Marius; Weber, Bernhard; Wright, Alan; Xu, Heping
aging: AIBILI; Artal, Pablo; Audo, Isabelle; Bandello, Francesco; Baraas, Rigmor; Barbur, John; Beattie, Renwick; Bergen, Arthur; Bird, Alan; Chakravarthy, Usha; Cordeiro, M Francesca; Cotter, Tom G.; De la Rosa, Enrique; Dedek, Karin; Dollfus, Hélène; Euler, Thomas; Findl, Oliver; Griciuc, Ana; Hammond, Chris; Hoffmann, Michael; Holz, Frank G.; Lagreze, Wolf; Lengyel, Imre; Lombardo, Marco; Lorenz, Birgit; Lütjen-Drecoll, Elke; Martin, Keith; Meek, Keith; Moore, Tony; Naumann, Gottfried; Navea, Amparo; Németh, János; Papageorgiou, Eleni; Research Group of Tunde Peto; Reinhard, Thomas; Stitt, Alan; Detorakis, Efstathios; Sennlaub, Florian; Tsilimbaris, Miltiadis; Jansonius, Nomdo; Riva, Charles; Rubin, Gary; Scanlon, Peter; Schmetterer, Leopold; Seeliger, Mathias; Stieger, Knut; Sørensen, Torben Lykke; Tassignon, Marie-José; Tepelus, Tudor-Cosmin; Thanos, Solon; Topouzis, Fotis
aging: visual performance: Barbur, John; Chakravarthy, Usha; Griciuc, Ana; Lombardo, Marco; Németh, János; Papageorgiou, Eleni; Detorakis, Efstathios; Rubin, Gary; Tassignon, Marie-José
antioxidants: Chakravarthy, Usha; Griciuc, Ana; Johnsen-Soriano, Siv; Miranda Sanz, María; Paquet-Durand, Francois; Tsilimbaris, Miltiadis; Romero, Francisco Javier; Sahaboglu, Ayse; Sancho-Pelluz, Javier; van Veen, Theo
apoptosis/cell death: Arango-Gonzalez, Blanca; Cordeiro, M Francesca; Cotter, Tom G.; Cottet, Sandra; De la Rosa, Enrique; Ekström, Per; Griciuc, Ana; Hauck, Stefanie; Heiduschka, Peter; Humphries, Peter; Joachim, Stephanie; Marigo, Valeria; Martin, Keith; Miranda Sanz, María; Reinhard, Thomas; Romero, Francisco Javier; Sancho-Pelluz, Javier; Ueffing, Marius; van Veen, Theo
carotenoids/carotenoid binding proteins: Larsen, Michael; Neuhauss, Stephan; Romero, Francisco Javier
clinical (human) or epidemiologic studies: biostatistics/epidemiology methodology: Butterworth, Jacqueline; Németh, János; Research Group of Tunde Peto; Prokofyeva, Elena; Reinhard, Thomas; Sennlaub, Florian; Scanlon, Peter; Topouzis, Fotis
clinical (human) or epidemiologic studies: health care delivery/economics/manpower: Research Group of Tunde Peto; Rubin, Gary; Scanlon, Peter
clinical (human) or epidemiologic studies: natural history: Holz, Frank G.; Larsen, Michael; Research Group of Tunde Peto; Prokofyeva, Elena; Jansonius, Nomdo; Schmetterer, Leopold; Wilhelm, Barbara
clinical (human) or epidemiologic studies: outcomes/complications: Butterworth, Jacqueline; Calonge, Margarita; Larsen, Michael; Research Group of Tunde Peto; Prokofyeva, Elena; Reinhard, Thomas; Jansonius, Nomdo; Rubin, Gary; Schmetterer, Leopold
clinical (human) or epidemiologic studies: prevalence/incidence: Butterworth, Jacqueline; Calonge, Margarita; Larsen, Michael; Research Group of Tunde Peto; Prokofyeva, Elena; Reinhard, Thomas; Jansonius, Nomdo; Rubin, Gary; Scanlon, Peter; Tassignon, Marie-José; Topouzis, Fotis; Zrenner, Eberhart
clinical (human) or epidemiologic studies: risk factor assessment: Bandello, Francesco; Calonge, Margarita; Guggenheim, Jez; Hammond, Chris; Larsen, Michael; Moore, Tony; Pastor, Jose-Carlos; Prokofyeva, Elena; Reinhard, Thomas; Detorakis, Efstathios; Jansonius, Nomdo; Scanlon, Peter; Schmetterer, Leopold; Topouzis, Fotis
clinical (human) or epidemiologic studies: systems/equipment/techniques: Bach, Michael; Calonge, Margarita; Cordeiro, M Francesca; Larsen, Michael; Németh, János; Research Group of Tunde Peto; Jansonius, Nomdo; Schmetterer, Leopold; Topouzis, Fotis; Wilhelm, Barbara
clinical (human) or epidemiologic studies: treatment/prevention assessment/controlled clinical trials: Arden, Geoffrey; Auricchio, Alberto; Calonge, Margarita; Cordeiro, M Francesca; Holz, Frank G.; Jager, Martine; Larsen, Michael; Navea, Amparo; Németh, János; Research Group of Tunde Peto; Prokofyeva, Elena; Reinhard, Thomas; Detorakis, Efstathios; Tsilimbaris, Miltiadis; Scanlon, Peter; Schmetterer, Leopold; Skorkovská, Karolína; Tepelus, Tudor-Cosmin; Topouzis, Fotis; Zrenner, Eberhart
clinical laboratory testing: Bach, Michael; Calonge, Margarita; Cordeiro, M Francesca; Coupland, Sarah; Findl, Oliver
clinical research methodology: Bach, Michael; Barbur, John; Beattie, Renwick; Calonge, Margarita; Hoffmann, Michael; Reinhard, Thomas; Zrenner, Eberhart
degenerations/dystrophies: Audo, Isabelle; Banfi, Sandro; Bhattacharya, Shomi; Biel, Martin; Cordeiro, M Francesca; De la Rosa, Enrique; Ekström, Per; Grau, Tanja; Grimm, Christian; Guenther, Elke; Hicks, David; Johnsen-Soriano, Siv; Kennedy, Breandan; Larsen, Michael; Marigo, Valeria; Strettoi, Enrica; Weber, Bernhard
image processing: Bethge, Matthias; Cordeiro, M Francesca; Dakin, Steven; Hoffmann, Michael; Reinhard, Thomas; Riva, Charles; Schaeffel, Frank
imaging/image analysis: clinical: Baraas, Rigmor; Beattie, Renwick; Cordeiro, M Francesca; Lengyel, Imre; Lorenz, Birgit; Moore, Tony; Németh, János; Research Group of Tunde Peto; Reinhard, Thomas; Tsilimbaris, Miltiadis; Scanlon, Peter; Schmetterer, Leopold
imaging/image analysis: non-clinical: Beattie, Renwick; Cordeiro, M Francesca; Dedek, Karin; Euler, Thomas; Hoffmann, Michael; Lagreze, Wolf; Lengyel, Imre; Lombardo, Marco; Meek, Keith; Research Group of Tunde Peto; Stitt, Alan; Riva, Charles; Seeliger, Mathias
imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound): Arango-Gonzalez, Blanca; Artal, Pablo; Audo, Isabelle; Bach, Michael; Bair, Wyeth; Bandello, Francesco; Banfi, Sandro; Baraas, Rigmor; Bovolenta, Paola; Calonge, Margarita; Chadderton, Naomi; Cordeiro, M Francesca; Cotter, Tom G.; Dakin, Steven; De la Rosa, Enrique; Dell'Orco, Daniele; Goureau, Olivier; Griciuc, Ana; Grimm, Christian; Guggenheim, Jez; Hammond, Chris; Hicks, David; Hoffmann, Michael; Holz, Frank G.; Jager, Martine; Kennedy, Breandan; Krishnakumar, Arjun; Langmann, Thomas; Larsen, Michael; Lengyel, Imre; Leveillard, Thierry; Lorenz, Birgit; Lütjen-Drecoll, Elke; Martin, Keith; Moore, Tony; Naumann, Gottfried; Németh, János; Paquet-Durand, Francois; Pastor, Jose-Carlos; Paulsen, Friedrich; Research Group of Tunde Peto; Prokofyeva, Elena; Reinhard, Thomas; Stitt, Alan; Detorakis, Efstathios; Kymionis, George; Jansonius, Nomdo; Vignali, Roberto; Rubin, Gary; Scanlon, Peter; Schmetterer, Leopold; Seeliger, Mathias; Stieger, Knut; Strauss, Olaf; Tassignon, Marie-José; Tepelus, Tudor-Cosmin; Topouzis, Fotis; Ueffing, Marius; van Veen, Theo; Weber, Bernhard
macula/fovea: Bach, Michael; Bergen, Arthur; Berger, Wolfgang; Dakin, Steven; Hoffmann, Michael; Holz, Frank G.; Larsen, Michael; Lotery, Andrew John; Tsilimbaris, Miltiadis; Scanlon, Peter; Sørensen, Torben Lykke
macular pigment: Hammond, Chris; Tsilimbaris, Miltiadis
nutritional factors
oxidation/oxidative or free radical damage: Cotter, Tom G.; Johnsen-Soriano, Siv; Miranda Sanz, María; Romero, Francisco Javier
photoreceptors: Ader, Marius; Arango-Gonzalez, Blanca; Arden, Geoffrey; Artal, Pablo; Auricchio, Alberto; Baraas, Rigmor; Berger, Wolfgang; Biel, Martin; Bovolenta, Paola; Bujakowska, Kinga; Cangiano, Lorenzo; Chadderton, Naomi; Cottet, Sandra; Dell'Orco, Daniele; Ekström, Per; Goureau, Olivier; Heiduschka, Peter; Hicks, David; Julien, Sylvie; Kamermans, Maarten; Kawasaki, Aki; Kennedy, Breandan; Kremers, Jan; Langmann, Thomas; Larsen, Michael; MacLaren, Robert; Marigo, Valeria; O'Driscoll, Ciara; Palfi, Arpad; Paquet-Durand, Francois; Sennlaub, Florian; Tsilimbaris, Miltiadis; Vignali, Roberto; Roska, Botond; Sahaboglu, Ayse; Sancho-Pelluz, Javier; Strettoi, Enrica; Ueffing, Marius; van Veen, Theo; Wijnholds, Jan; Wissinger, Bernd; Wolfrum, Uwe; Zeitz, Christina
photoreceptors: visual performance: Cangiano, Lorenzo; Kawasaki, Aki; Kremers, Jan
quality of life: Bach, Michael; Papageorgiou, Eleni; Tsilimbaris, Miltiadis; Skorkovská, Karolína
radiation damage: light/UV: Hafezi, Farhad; Jager, Martine
reading: Dakin, Steven; Rubin, Gary
receptors: Ader, Marius; Arango-Gonzalez, Blanca; Arden, Geoffrey; Artal, Pablo; Auricchio, Alberto; Baraas, Rigmor; Berger, Wolfgang; Biel, Martin; Bovolenta, Paola; Bujakowska, Kinga; Cangiano, Lorenzo; Chadderton, Naomi; Cordeiro, M Francesca; Cottet, Sandra; De la Rosa, Enrique; Dell'Orco, Daniele; Ekström, Per; Goureau, Olivier; Griciuc, Ana; Grimm, Christian; Guenther, Elke; Heiduschka, Peter; Hicks, David; Julien, Sylvie; Kamermans, Maarten; Kawasaki, Aki; Kennedy, Breandan; Kremers, Jan; Krishnakumar, Arjun; Langmann, Thomas; Larsen, Michael; Lütjen-Drecoll, Elke; MacLaren, Robert; Marigo, Valeria; O'Driscoll, Ciara; Palfi, Arpad; Paquet-Durand, Francois; Picaud, Serge; Sennlaub, Florian; Tsilimbaris, Miltiadis; Vignali, Roberto; Roska, Botond; Sahaboglu, Ayse; Sancho-Pelluz, Javier; Schaeffel, Frank; Strauss, Olaf; Strettoi, Enrica; Ueffing, Marius; van Veen, Theo; Veruki, Margaret; Vitanova, Liliya; Wässle, Heinz; Wijnholds, Jan; Wissinger, Bernd; Wolfrum, Uwe; Zeitz, Christina
receptors: pharmacology/physiology: Guenther, Elke; Picaud, Serge; Schaeffel, Frank; Vitanova, Liliya
vascular endothelial growth factor: Bandello, Francesco; Calonge, Margarita; Jager, Martine; Lorenz, Birgit; Stitt, Alan
Macular Pigment: Hammond, Chris; Tsilimbaris, Miltiadis
Lutein / Zeaxanthin
Stiles-Crawford
Photoreceptors: Ader, Marius; Arango-Gonzalez, Blanca; Arden, Geoffrey; Artal, Pablo; Auricchio, Alberto; Baraas, Rigmor; Berger, Wolfgang; Biel, Martin; Bovolenta, Paola; Bujakowska, Kinga; Cangiano, Lorenzo; Chadderton, Naomi; Cottet, Sandra; Dell'Orco, Daniele; Ekström, Per; Goureau, Olivier; Heiduschka, Peter; Hicks, David; Julien, Sylvie; Kamermans, Maarten; Kawasaki, Aki; Kennedy, Breandan; Kremers, Jan; Langmann, Thomas; Larsen, Michael; MacLaren, Robert; Marigo, Valeria; O'Driscoll, Ciara; Palfi, Arpad; Paquet-Durand, Francois; Sennlaub, Florian; Tsilimbaris, Miltiadis; Vignali, Roberto; Roska, Botond; Sahaboglu, Ayse; Sancho-Pelluz, Javier; Strettoi, Enrica; Ueffing, Marius; van Veen, Theo; Wijnholds, Jan; Wissinger, Bernd; Wolfrum, Uwe; Zeitz, Christina