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Theo van Veen

1975-1981 PhD studies at Lund University
1981 PhD exam at Lund University
1991 Professor and chairman of dept of animal morphology at Göteborg University
1994-1999 Prefekt (director) of the Institute of Zoology (3 departments)
2000 Guest Professor of exp. Ophthalmology at Lund University
2004 Full professor of exp. Ophthalmology
2007 - Senior Consultant and group leader at the division of Experimental Ophthalmology Tübingen University

Documents

CV of Theo van Veen [pdf]

Scientific Interests

  • To investigate, and interfere with, the signals of degenerating photoreceptors that lead to death or survival.
  • To improve neuroprotection through new combinations / concentrations of known and novel rescue factors.
  • To investigate the role of glia cell activation in the process of photoreceptor cell death and survival

Further Activities

  • CEO for two small companies

Methodology

  • Histopathology
  • Long term retinal organ cultures
  • Immunohistochemistry
  • Histochemistry
  • Western blot
  • Q-PCR
  • Micro Array

Memberships

  • Association for Research in Vision and Ophthalmology  (ARVO)
  • ICER
  • Neuroscience
Theo van Veen
Theo van Veen

Contact

University of Tübingen

Centre for Ophthalmology
Institute for Ophthalmic Research

Roentgenweg 11
72076 Tuebingen
German

Phone: +49-7071-29-84020
Fax: +49-7071-29-5777

Email:
Theo.van_Veen[at]med.lu.se

Publications

  1. van Veen T, Östholm T, Gierschik P, Spiegel A, Somers B, Klein DC .
    α-Transducin immunoreactivity in retinae and sensory pineal organs of adult vertebrates.
    Proc Natl Acad Sci USA 83: 912-916, 1986
  2. Szél A, van Veen T, Röhlich P.
    Retinal cone differentiation.
    Nature 370: 336, 1994
  3. Röhlich P, van Veen T, Szél A
    Two different visual pigments in one retinal cone cell.
    Neuron 13: 1159-1166, 1994
  4. Caffe AR, Söderpalm AK, Holmqvist I, van Veen T
    A combination of CNTF and BDNF rescues rd photoreceptors but changes rod differentiation in the presence of RPE in retinal explants.
    Invest. Ophthalmol. Vis. Science 42(1):275-82, 2001
  5. Hauck SM, Ekström PA, Ahuja-Jensen P, Suppmann S, Paquet-Durand F, van Veen T, Ueffing M.
    Differential modification of phosducin protein in degenerating rd1 retina is associated with constitutively active Ca2+/calmodulin kinase II in rod outer segments.
    Mol Cell Proteomics. 2006 Feb;5(2):324-36.
  6. Ahuja P, Caffé AR, Ahuja S, Ekström P, van Veen T.
    Decreased glutathione transferase levels in rd1/rd1 mouse retina: replenishment protects photoreceptors in retinal explants.
    Neuroscience. 2005;131(4):935-43.
  7. Azadi S, Johnson LE, Paquet-Durand F, Perez MT, Zhang Y, Ekström PA, van Veen T.
    CNTF+BDNF treatment and neuroprotective pathways in the rd1 mouse retina.
    Brain Res. 2007 Jan 19;1129(1):116-29.
  8. Sanz MM, Johnson LE, Ahuja S, Ekström PA, Romero J, van Veen T.
    Significant photoreceptor rescue by treatment with a combination of antioxidants in an animal model for retinal degeneration.
    Neuroscience. 2007 Mar 30;145(3):1120-9
  9. Paquet-Durand F, Silva J, Talukdar T, Johnson LE, Azadi S, van Veen T, Ueffing M, Hauck SM, Ekström PA.
    Excessive activation of poly(ADP-ribose) polymerase contributes to inherited photoreceptor degeneration in the retinal degeneration 1 mouse.
    J Neurosci. 2007 Sep 19;27(38):10311-9.
  10. Ahuja S, Ahuja-Jensen P, Johnson LE, Caffé AR, Abrahamson M, Ekström PA, van Veen T
    rd1 Mouse retina shows an imbalance in the activity of cysteine protease cathepsins and their endogenous inhibitor cystatin C.
    Invest Ophthalmol Vis Sci. 2008 Mar;49(3):1089-96.

Research Groups

People

Related Research Groups

antioxidants
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apoptosis/cell death
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apoptosis/cell death
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extracellular matrix
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growth factors/growth factor receptors
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immunohistochemistry
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neuroprotection
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photoreceptors
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retinal culture
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retinal degenerations: hereditary
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retinitis pigmentosa
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degeneration
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animal models
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