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Centre for Vision & Vascular Science

The Centre for Vision & Vascular Science (CVVS) at Queen's University Belfast is a focused research grouping within the School of Medicine, Dentistry & Biomedical Science (MDBMS). The largest component of our centre is vision-related research which has emerged as a leading programme in academic Ophthalmology in the UK.

This group’s current research interests fall into three main themes:

  1. The pathogenic role of advanced glycation endproducts (AGEs) and RAGE in diabetic retinopathy
  2. Retinal angiogenesis including harnessing the regenerative potential of endothelial progenitor cells for ischaemic retinopathies
  3. The pathobiology of age-related retinal dysfunction and RPE biology

Methodology

  • Molecular cell biology in in vitro and in vivo models of retinal disease and clinical material

Group Leader

Alan Stitt
[more information]

Contact

Queen’s University Belfast

Centre for Vision & Vascular Science,
School of Medicine, Dentistry & Biomedical Science
Royal Victoria Hospital

Belfast BT12 6BA
Northern Ireland UK

Phone: 011 44 (0) 28-90632546
Fax: 011 44 (0) 28-90632699

Email:
a.stitt[at]qub.ac.uk

Website:
www.qub.ac.uk/research-centres/CentreforVisionandVascularSciences/

Current Research Projects

  • Project 1:
    Cell Therapy for the vasodegenerative stages of diabetic retinopathy and ischaemic retinopathies
  • Project 2:
    Pro-inflammatory signalling of RAGE in the retina
  • Project 3:
    Neuroglial protective and vasoregenerative properties of erythropoietin
  • Project 4:
    The use of Raman spectroscopy to detect chemical modifications in diabetic and ageing retina
  • Project 5:
    The pathogenic role of AGEs in diabetic and age-related retinopathies

Research Groups

People

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aging
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diabetic retinopathy
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hypoxia
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imaging/image analysis: non-clinical
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inflammation
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ischemia
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regeneration
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retinal degenerations: cell biology
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retinopathy of prematurity
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vascular endothelial growth factor
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vascular occlusion/vascular occlusive disease
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advanced glycation
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endothelial progenitor cells
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RAGE
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raman spectroscopy
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therapeutic angiogenesis
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