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Cell and Developmental Biology Unit

Members of the research group:

Molecular embryology: misexpression and knockdown assays by microinjections/lipofection of mRNA and/or morpholino in developing Xenopus embryos; immunostaining and in situ hybridization
Cell culture and molecular biology techniques: transfection and gene expression analysis (cell transfection, RT-PCR, immunostaining and fluorescence analysis, confocal microscopy)

Cooperation 1:
Prof William Harris, Physiology Development and Neuroscience, University of Cambridge, U.K.
Cooperation 2:
Dr Jochen Wittbrodt, EMBL, Heidelberg
Cooperation 3:
Dr Simona Casarosa, Centre for Integrative Biology, Università di Trento, Italy
Cooperation 4:
Prof Rongqiao He, Chinese Academy of Sciences, Beijing
Cooperation 5:
Dr Vania Broccoli, DIBIT, HS Raffaele, Milan, Italy

Robert Vignali
[more information]

Administration:
Dipartimento di Biologia
via Luca Ghini 5
56126 Pisa

Laboratoy:
Via G. Carducci 13
56010 GHEZZANO (PISA)
Italy

Phone: 0039-050-2211497
Fax: 0039-050-2211495

Project 1:
How to drive embryonic stem cells toward a retinal fate: role of eye specific transcription factors
Project 2:
Molecular mechanisms of action of homeobox transcription factors in retinal development and cell commitment
Project 3:
Role of micro RNA in retinal cell commitment
Project 4:
Cell cycle dependent regulation of cell polarity and homeobox factors in the retina
Project 5:
Multipotency of retinal stem cells: role of RX1 transcription factor and its target genes