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Centre for Vision and Vascular Science

Our interests focus on the role played by intracellular Ca2+ in the control of contractility in smooth muscle, particularly in retinal microvessels. This includes consideration of the effects of localised Ca2+-sparks, cell-wide Ca2+-waves and oscillations, and cell-to-cell spread of Ca2+-signals within microvessels.

Much of this work is part of longstanding investigations into how diabetes, a major cause of blindness, affects these small blood vessels, and is carried out as part of an internationally recognised group of scientists studying the mechanisms responsible for diabetic retinopathy.

Methodology

  • Electrophysiology.
  • Confocal Ca imaging
  • In vivo vascular imaging using cSLO techniques

Scientific Cooperations

  • Cooperation 1
    Within the Helmholtz Center Munich: Institutes of Experimental Genetics (Prof. Hrabé de Angelis) and Epidemiology (Prof. Wichmann)
  • Cooperation 2
    Institute of Genetics, University of Madras/India (Prof. Santhiya)
  • Cooperation 3
    The Center for Human Genetics - Marshfield Clinic Research Foundation; Marshfield /WI-USA (Cathrine McCarty, PhD)
  • Cooperation 4
    University Eye Clinic Giessen (Dr. Schmidt)

Group Leader

Graham McGeown
[more information]

Contact

Queen's University Belfast

Institute of Clinical Science A, Royal Victoria Hopsital
Grosvenor Road
BT12 6BA Belfast
Northern Ireland

Phone: +44 (0)28 90632629
Fax: +44 (0)28 90632699

Email:
g.mcgeown[at]qub.ac.uk

Website:
www.qub.ac.uk/research-centres/CentreforVisionandVascularSciences/

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