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Retinal function and metabolism

The target is to study the relation between function, metabolism, and perfusion in the retina under various types of metabolic challenges, including hypoperfusion, hypoxia, and unstable glycemia, as seen in the diabetic retinopathy and the ocular ischemic syndrome, and in the presence of various genetic defects such as retinitis pigmentosa.

The group conducts clinical and experimental research in retinopathy and noninvasive techniques for assessment of retinal function and structure.

Methodology

  • Electroretinography
  • Optical coherence tomography
  • Histology
  • Respirometry
  • Proteomics

Scientific Cooperations

  • Cooperation 1:
    University of Lund (Sten Andreasson)
  • Cooperation 2:
    Penn State University (Thomas W. Gardner)
  • Cooperation 3:
    University of Aarhus (Henrik Vorum)
  • Cooperation 4:
    Technical University of Denmark (Anders Bjarklev)
  • Cooperation 5:
    University of Oslo (Bjørn Nicolaisen)

Group Leader

Michael Larsen
[more information]

Contact

University of Copenhagen, Glostrup Hospital

Department of Ophthalmology

Ndr. Ringvej 572600 GlostrupDenmark

Phone-Number:
+45 4323 4834

Fax-Number:
+45 4323 4669

Email:
miclar01[at]glo.regionh.dk

Website:
www.glostruphospital.dk/menu/Afdelinger/Oejenafdelingen/Oculus/

Current Research Projects

  • Project 1:
    Long-term retinal adaptation to normoglycemia
  • Project 2:
    Structure and function of the retina in chronic extreme hypoperfusion
  • Project 3:
    Genetics of central serous chorioretinopathy
  • Project 4:
    Genetics of small hard drusen
  • Project 5:
    Retinal autofluorescence in degenerative disease

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