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Retinal Repair and Regeneration Research Group

We investigate the cellular and molecular mechanisms that promote differentiation of human Müller  stem cells into different types of retinal neurons.  We also examine methods that may be potentially used for functional transplantation of these cells into degenerated retina.

Methodology

We use various molecular biology approaches as well as in vivo cell transplantation into the retina of animal models of retinal degeneration. We assess retinal function using electrophysiological techniques.

Scientific Cooperations

  • Cooperation 1
    Dr Maria-Teresa Perez- Sweden
  • Cooperation 2
    Prof Andreas Reichenbach, Leipzig
  • Cooperation 3
    Dr Andreas Brigmann, Leipzig
  • Cooperation 4
    Gerd Geerling, Lubeck

Current Research Projects

  • Project 1
    Preclinical validation of the regenerative potential of retinal ganglion cells (RGC) derived from Müller stem cells
  • Project 2
    Design of nano-scaffolds for retinal cell transplantation
  • Project 3
    Design and optimization of cellular scaffolds for retinal ganglion cell replacement
  • Project 4
    Searching for better integration of transplanted Müller stem cells

Group Leader

G. Astrid Limb
[more information]

Contact

UCL Institute of Ophthalmology

11-43 Bath Street
EC1V 9EL London
UK

Phone: + 44 207 608 6974
Fax: +44 207 608 6887

Email:
g.limb[at]ucl.ac.uk

Website
http://www.ucl.ac.uk/ioo

Research Groups

People

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