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Dynamin-binding protein linked to congenital cataracts

Cataracts, a condition in which the eyes' natural lenses get clouded, are the most common cause of vision loss in older people and can be corrected by routine surgery.

But congenital cataracts, which occur in infants and children, are particularly serious since they can inhibit visual development leading to permanent vision loss or impairment that cannot be entirely reversed with cataract surgery. A new study has now found compelling evidence that links dynamin-binding protein (DNMBP) to congenital bilateral cataracts and severe vision loss. The study appears in the American Journal of Human Genetics.