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Microglia, immune cells of the central nervous system, shown to regulate neuroinflammation

A research team at Massachusetts Eye and Ear has shown that microglia, the primary immune cells of the central nervous system—including the retina of the eye—serve as "gatekeepers," or biosensors and facilitators, of neuroinflammation in a preclinical model of autoimmune uveitis.

Uveitis is one of the leading causes of blindness, accounting for approximately 10% of significant visual impairment worldwide.