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Experimental Ophthalmology

The main focus of our research is the experimental therapy of retinal degenerations. This includes neuroprotection as well as stem cell transplantation in rodent models with induced and genetically engineered retinal damage.

Furthermore, as understanding the underlying pathophysiology is crucial for the success of regenerative approaches we characterize pathways of programmed cell death involved in pharmaceutically induced retinal degeneration.

Identification of adult stem cells and their differentiation towards retinal lineages is also part of our research activities.

Methodology

  • Rodent models of induced and inherited retinal degeneration
  • Molecular biology & cell culture
  • Microsurgery & microscopy incl. immunohistochemistry

Scientific Cooperations

  • Cooperation 1
    Henry J. Kaplan, Dept. of Ophthalmology, University of Louisville, USA
  • Cooperation 2
    Andreas Reichenbach, University of Leipzig, Germany
  • Cooperation 3
    Anna Jazwinska, University of Fribourg, Switzerland
  • Cooperation 4
    Stephen Leib, University of Bern, Switzerland
  • Cooperation 5
    Hans Ruedi Widmer, Inselspital, University of Bern, Switzerland

Group Leader

Volker Enzmann
[more information]

Contact

University of Bern

Inselspital

Freiburgstrasse 14
3010 Bern
Switzerland

Phone: +41316328935
Fax: +41316324882

E-mail:
volker.enzmann[at]insel.ch

Website:
www.augenheilkunde.insel.ch

Current Research Projects

  • Project 1
    Neuroprotection in retinal degeneration
  • Project 2
    Animal models with pharmacologically induced retinal degeneration
  • Project 3
    Characterization of  a new type of progenitor cells in the adult retina
  • Project 4
    Regenerative therapy with bone marrow-derived stem cells for retinal degeneration

Research Groups

People

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