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Vanessa Andrés-Guerrero

Current Research Projects

  • Peptide-based nanoparticles as ocular drug delivery vehicles (PANOPTES). 
  • Development of new treatments and ophthalmic formulations for dry eye syndrome.

Methodology

  • HPLC-UV, HPLC-MS, GPC, DSC, rheology, osmolarity, surface tension and scanning electron microscopy.
  • Intraocular pressure, tolerance.
  • In vitro studies in culture cells (cornea, conjunctiva and macrophage cells)
  • In vivo studies in rabbits and rats.

Selected Publications

  1. Andrés-Guerrero V., Herrero-Vanrell R.
    Ocular drug absorption by topical route. Role of conjunctiva.
    Arch. Soc. Esp. Oftalmol. 2008;83:683-686. [article in spanish]
  2. Andrés-Guerrero V, Alarma-Estrany P, Molina-Martínez IT, Peral A, Herrero-Vanrell R, Pintor J.
    Ophthalmic formulations of the Intraocular Hypotensive Melatonin Agent 5-MCA-NAT.
    Experimental Eye Research, 2009;88:504-511.
  3. Andrés-Guerrero V, Molina-Martínez IT, Peral A, de Las Heras B, Pintor J, Herrero-Vanrell R.
    The use of mucoadhesive polymers to enhance the hypotensive effect of a melatonin analog (5-MCA-NAT) in rabbit eyes.
    Investigative Ophthalmology & Visual Science 2011;52(3):1507-151.
  4. Andrés-Guerrero V, Vicario-de-la-Torre M, Molina-Martínez IT, Benítez-del-Castillo JM, García-Feijoo J, Herrero-Vanrell R.
    Comparison of the in vitro tolerance and in vivo efficacy of traditional timolol maleate eye drops versus new formulations with bioadhesive polymers.
    Investigative Ophthalmology & Visual Science 2011;52(6):3548-56.

Vanessa Andrés-Guerrero
Image Vanessa Andrés-Guerrero

Research Group

Design and evaluation of ophthalmic products and biomaterials

[Diseño y Evaluación de Productos y Biomateriales Oftálmicos] - UCM 920415

Contact

Universidad Complutense de Madrid

Facultad de Farmacia

Plaza Ramón y Cajal s/n
28040 Madrid
Spain

Phone: +34 913 941-727
Fax: +34 913 941-736

E-mail:
vandres[at]farm.ucm.es

Website:
http://www.ucm.es

Research Groups

People

Related Research Groups

cell survival
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circadian rhythms
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conjunctiva
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cornea: tears/tear film/dry eye
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drug toxicity/drug effects
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glaucoma
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intraocular pressure
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neuroprotection
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retina
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