Current Research Projects
- Peptide-based nanoparticles as ocular drug delivery vehicles (PANOPTES).
- Development of new treatments and ophthalmic formulations for dry eye syndrome.
Methodology
- HPLC-UV, HPLC-MS, GPC, DSC, rheology, osmolarity, surface tension and scanning electron microscopy.
- Intraocular pressure, tolerance.
- In vitro studies in culture cells (cornea, conjunctiva and macrophage cells)
- In vivo studies in rabbits and rats.
Selected Publications
- Andrés-Guerrero V., Herrero-Vanrell R.
Ocular drug absorption by topical route. Role of conjunctiva.
Arch. Soc. Esp. Oftalmol. 2008;83:683-686. [article in spanish] - Andrés-Guerrero V, Alarma-Estrany P, Molina-Martínez IT, Peral A, Herrero-Vanrell R, Pintor J.
Ophthalmic formulations of the Intraocular Hypotensive Melatonin Agent 5-MCA-NAT.
Experimental Eye Research, 2009;88:504-511. - Andrés-Guerrero V, Molina-Martínez IT, Peral A, de Las Heras B, Pintor J, Herrero-Vanrell R.
The use of mucoadhesive polymers to enhance the hypotensive effect of a melatonin analog (5-MCA-NAT) in rabbit eyes.
Investigative Ophthalmology & Visual Science 2011;52(3):1507-151. - Andrés-Guerrero V, Vicario-de-la-Torre M, Molina-Martínez IT, Benítez-del-Castillo JM, García-Feijoo J, Herrero-Vanrell R.
Comparison of the in vitro tolerance and in vivo efficacy of traditional timolol maleate eye drops versus new formulations with bioadhesive polymers.
Investigative Ophthalmology & Visual Science 2011;52(6):3548-56.
Vanessa Andrés-Guerrero |
Research Group
Design and evaluation of ophthalmic products and biomaterials
[Diseño y Evaluación de Productos y Biomateriales Oftálmicos] - UCM 920415
Contact
Universidad Complutense de Madrid
Facultad de Farmacia
Plaza Ramón y Cajal s/n
28040 Madrid
Spain
Phone: +34 913 941-727
Fax: +34 913 941-736
E-mail:
vandres[at]farm.ucm.es
Website:
http://www.ucm.es
Research Groups
People