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Sandra Cottet

Short CV

Education

1995-1999 PhD in Molecular and Cellular Biology, Lausanne University

1993-1994

Master degree in Biology, Institute of Animal Biology, Lausanne University
1989-1993 Bachelor degree in Sciences, Lausanne University, Switzerland

Positions

Since 2007 Group leader, Institute for Research in Ophthalmology (IRO), Sion, Switzerland
2004-2007 Senior scientist, Institute for Research in Ophthalmology (IRO), Sion, Switzerland

2003-2004

R&D Project leader at BELAIR Biotechnology – Scientific Park, Swiss Federal Institute of Technology (EPFL), Switzerland
1999-2003 Postdoctoral research fellow at the Institute of Pharmacology and Toxicology, University of Lausanne, Switzerland

Documents

CV of Sandra Cottet [pdf]

Scientifc Interest

Cell death and survival mechanisms in inherited retinal degeneration

Memberships

  • ZMG: Swiss Society for Cell Biology, Molecular Biology and Genetics
  • ARVO: Association for Research in Vision and Ophthalmology
  • ISOCB: International Society of Ocular Cell Biology
  • ECDO: European Cell Death Organization
Sandra Cottet
Sandra Cottet

Research Group

Institute for Research in Ophthalmology - IRO

[more information]

Contact

Institute for Research in Ophthalmology

Avenue Grand-Champsec 64
1950 Sion
Switzerland

Phone: +41 (0)27 205 79 06
Fax: +41 (0)27 205 79 01

E-mail:
sandra.cottet[at]irovision.ch

Website:
www.irovision.ch

Key Publications

  1. Hamann S., Métrailler S, Schorderet DF and Cottet S.
    Analysis of the cytoprotective role of α-crystallins in cell survival and implication of the αA-crystallin C-terminal extension domain in preventing Bax-induced apoptosis.
    In press in PLoS ONE
  2. Métrailler S, Schorderet DF and Cottet S. (2012)
    Early apoptosis of rod photoreceptors in Rpe65-/- mice is associated with the upregulated expression of lysosomal-mediated autophagic genes.
    Experimental Eye Research 96: 70-81
  3. Escher P., Schorderert DF. and Cottet S. (2011)
    Altered expression of the transcription factor Mef2c during retinal degeneration in Rpe65-/- mice.
    Investigative Ophthalmology & Visual Science 52: 5933-5940
  4. Le Carré J, Schorderet DF and Cottet S. (2011)
    Altered expression of β-galactosidase-1-like protein 3 (Glb1l3) in Rpe65-/- mouse model of Leber's congenital amaurosis.
    Molecular Vision 17: 1287-1297
  5. Hamann S., Schorderet DF. and Cottet S. (2009)
    Bax-induced Apoptosis in Leber’s Congenital Amaurosis: A Dual Role in Rod and Cone Degeneration.
    PLoS ONE 4(8): e6616
  6. Cottet S. and Schorderet DF. (2009)
    Mechanisms of apoptosis in Retinitis Pigmentosa.
    Current Molecular Medicine 9:375-383
  7. Escher P., Cottet S., Aono S., Oohira A. and Schorderet DF. (2008)
    Differential neuroglycan C expression during retinal degeneration in Rpe65-/- mice.
    Molecular Vision 14: 2126-35
  8. Cottet S. and Schorderet DF. (2008)
    Triggering of Bcl-2-related pathway is associated with apoptosis of photoreceptors in Rpe65-/- mouse model of Leber's Congenital Amaurosis.
    Apoptosis 13: 329-42
  9. Schorderet DF., Cottet S., Lobrinus JA., Borruat FX., Balmer A., and Munier FL. (2007)
    Retinopathy in Danon disease.
    Archives of Ophthalmology 125: 231-6
  10. Cottet S., Michaut L., Boisset G., Schlecht U., Gehring W., and Schorderet DF. (2006)
    Biological characterization of gene response in Rpe65-/- mouse model of Leber’s congenital amaurosis during progression of the disease.
    FASEB Journal 20: 2036-49.

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