Short CV
2007 – present | Group leader position, Department of Genetics, Institut de la Vision, INSERM, Paris, France |
2003-2007 | Postdoctoral fellow, Institute of Medical Genetics, Division of Medical Molecular Genetics and Gene Diagnostics, University Zurich, Switzerland |
1999-2003 | PhD student, Department of Human Molecular Genetics, Max-Planck-Institute for Molecular Genetics, Berlin, Germany, Institute of Medical Genetics, Division of Medical Molecular Genetics and Gene Diagnostics, University Zurich, Switzerland, Free University Berlin, Germany |
- Phenotype-genotype correlations in patients with different eye diseases
- Congenital stationary night blindness
- Signalling from photoreceptors to bipolar cells
Memberships
- American Society of Human Genetics (ASHG)
- Association for Research in Vision and Ophthalmology (ARVO)
- International Society for Genetic Eye Disease & Retinoblastoma (ISGED)
Ad hoc paper reviewer:
- Investigative Ophthalmology and Visual Sciences
- Molecular Vision
- Human Genetics
- GeneReviews
Christina Zeitz |
Research Group
Department of Genetics
Identification of gene defects leading to non progressive or progressive ocular eye diseases from A(udo)-Z(eitz)
[more information]
Key Publications
- Leroy BP, Budde B, Wittmer M, De Baere E, Berger W, Zeitz C (2008)
A common NYX mutation in Flemish patients with X-linked CSNB. BJO.
Published online July 2008.
- Zeitz C*, Gross AK*, Leifert D, Kloeckener-Gruissem B, McAlear SD, Lemke J, Neidhardt J, Berger B (2008)
A novel constitutively active rhodopsin mutation (p.Ala295Val) causes autosomal dominant CSNB.
Invest. Ophthalmol. Vis. Sci. 49: 4105-4114.
- Zeitz C (2007)
Molecular genetics and protein function involved in nocturnal vision.
Exp Rev of Ophthalmol. 2: 467-485.
- Zeitz C, Forster U, Neidhardt J, Feil S, Kälin S, Leifert D, Flor PJ, Berger W (2007)
Night blindness associated mutations in the ligand-binding, cysteine-rich and transmembrane domains of the metabotropic glutamate receptor 6 abolish protein trafficking.
Human Mut, 28: 771-786.
- Wycisk KA*, Zeitz C*, Feil S, Wittmer M, Forster U, Neidhardt J, Wissinger B, Zrenner E, Wilke R, Kohl S, Berger W (2006)
Mutation in the auxiliary calcium channel subunit CACNA2D4 causes a mild form of autosomal recessive cone dystrophy.
Am J Hum Genet, 79: 973-977.
- Bahadori R*, Biehlmaier O*, Zeitz C*, Labhart T, Makhankov YV, Forster U, Gesemann M, Berger W, Neuhauss SCF (2006)
Nyctalopin is essential for synaptic transmission in the cone dominated zebrafish retina.
Eur J Neurosci, 24: 1664-1674.
- Zeitz C, Kloeckener-Gruisem B, Forster U, Kohl S, Magyar I, Wissinger B, Mátyás G, Borruat F, Schorderet DF, Zrenner E, Munier FL, Berger W (2006)
Mutations in CABP4, the gene encoding the Ca2+-binding protein 4, cause autosomal recessive night blindness.
Am J Hum Genet, 79: 657-667.
- Zeitz C*, Genderen M*, Neidhardt J, Luhmann UFO, Hoeben F, Forster U, Wycisk K, Mátyás G, Hoyng CB, Riemslag F, Meire F, Cremers FPM, Berger W (2005)
Mutations in GRM6 cause autosomal recessive congenital stationary night blindness with a distinctive scotopic 15 Hz flicker electroretinogram (ERG).
Invest Ophthalmol Vis Sci, 46: 4328-4335.
- Zeitz C*, Scherthan H*, Freier S, Feil S, Suckow V, Schweiger S, and Berger W (2003)
Functional characterization of protein motifs of NYX (nyctalopin on chromosome X) in mouse and man.
Invest Ophthalmol Vis Sci, 44: 4184-4191.
- Pusch C*, Zeitz C*, Brandau O*, Pesch K, Achatz H, Feil S, Scharfe C, Maurer J, Jacobi FK, Pinckers A, Andreasson S, Hardcastle AJ, Wissinger B, Berger W, and Meindl A (2000)
The complete form of X-linked congenital stationary night blindness is caused by mutations in a gene encoding a leucine-rich repeat protein.
Nature Genet, 26: 324-327.
* These authors contributed equally to this work
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