Short CV
Education
1995-1999 | PhD in Molecular and Cellular Biology, Lausanne University |
1993-1994 | Master degree in Biology, Institute of Animal Biology, Lausanne University |
1989-1993 | Bachelor degree in Sciences, Lausanne University, Switzerland |
Positions
Since 2007 | Group leader, Institute for Research in Ophthalmology (IRO), Sion, Switzerland |
2004-2007 | Senior scientist, Institute for Research in Ophthalmology (IRO), Sion, Switzerland |
2003-2004 | R&D Project leader at BELAIR Biotechnology – Scientific Park, Swiss Federal Institute of Technology (EPFL), Switzerland |
1999-2003 | Postdoctoral research fellow at the Institute of Pharmacology and Toxicology, University of Lausanne, Switzerland |
Scientifc Interest
Cell death and survival mechanisms in inherited retinal degeneration
Memberships
- ZMG: Swiss Society for Cell Biology, Molecular Biology and Genetics
- ARVO: Association for Research in Vision and Ophthalmology
- ISOCB: International Society of Ocular Cell Biology
- ECDO: European Cell Death Organization
Sandra Cottet |
Key Publications
- Hamann S., Métrailler S, Schorderet DF and Cottet S.
Analysis of the cytoprotective role of α-crystallins in cell survival and implication of the αA-crystallin C-terminal extension domain in preventing Bax-induced apoptosis.
In press in PLoS ONE - Métrailler S, Schorderet DF and Cottet S. (2012)
Early apoptosis of rod photoreceptors in Rpe65-/- mice is associated with the upregulated expression of lysosomal-mediated autophagic genes.
Experimental Eye Research 96: 70-81 - Escher P., Schorderert DF. and Cottet S. (2011)
Altered expression of the transcription factor Mef2c during retinal degeneration in Rpe65-/- mice.
Investigative Ophthalmology & Visual Science 52: 5933-5940 - Le Carré J, Schorderet DF and Cottet S. (2011)
Altered expression of β-galactosidase-1-like protein 3 (Glb1l3) in Rpe65-/- mouse model of Leber's congenital amaurosis.
Molecular Vision 17: 1287-1297 - Hamann S., Schorderet DF. and Cottet S. (2009)
Bax-induced Apoptosis in Leber’s Congenital Amaurosis: A Dual Role in Rod and Cone Degeneration.
PLoS ONE 4(8): e6616 - Cottet S. and Schorderet DF. (2009)
Mechanisms of apoptosis in Retinitis Pigmentosa.
Current Molecular Medicine 9:375-383 - Escher P., Cottet S., Aono S., Oohira A. and Schorderet DF. (2008)
Differential neuroglycan C expression during retinal degeneration in Rpe65-/- mice.
Molecular Vision 14: 2126-35 - Cottet S. and Schorderet DF. (2008)
Triggering of Bcl-2-related pathway is associated with apoptosis of photoreceptors in Rpe65-/- mouse model of Leber's Congenital Amaurosis.
Apoptosis 13: 329-42 - Schorderet DF., Cottet S., Lobrinus JA., Borruat FX., Balmer A., and Munier FL. (2007)
Retinopathy in Danon disease.
Archives of Ophthalmology 125: 231-6 - Cottet S., Michaut L., Boisset G., Schlecht U., Gehring W., and Schorderet DF. (2006)
Biological characterization of gene response in Rpe65-/- mouse model of Leber’s congenital amaurosis during progression of the disease.
FASEB Journal 20: 2036-49.
Research Groups
People