Per Ekström is associate professor at the Department of Ophthalmology Research, Lund University in Sweden.
Short CV
Degrees etc.:
- Accepted as ”docent” (Assoc. Prof.) in Animal Physiology, Lund Univ., 1992.
- PhD, Animal Physiology, Lund Univ., 1987.
Current position:
- Researcher, Ophthalmology, Dept. Clinical Sciences, Lund Univ., 2001 and onwards.
Previous positions:
- Reader, Animal Physiology, Lund Univ., 1995 – 2001.
- Post-doctoral fellow, Animal Physiology, Lund Univ. 1989-1994.
- Post-doctoral studies, Dept. Physiology and Pharmacology, Nottingham Univ., UK, 1988.
- Mechanisms of hereditary retinal degeneration;
- Neuronal cell death mechanisms;
- Neuroprotection in hereditary retinal degeneration
- Association for Research in Vision and Ophthalmology (ARVO)
- American Society for Biochemistry and Molecular Biology (ASBMB)
- The Society for Neuroscience (SFN)
Research Group
Per Ekström
Key Publications
- Kaur J, Mencl S, Sahaboglu A, Farinelli P, van Veen T, Zrenner E, Ekström P, Paquet-Durand F, Arango-Gonzalez B (2011).
Calpain and PARP activation during photoreceptor cell death in P23H and S334ter rhodopsin mutant rats.
PLoS One 6;e22181. - Paquet-Durand F, Sanges D, McCall J, Silva J, van Veen T, Marigo V, Ekström P (2010).
Photoreceptor rescue and toxicity induced by different calpain inhibitors.
Journal of Neurochemistry, 115:930-940. - Sancho-Pelluz J, Alavi MV, Sahaboglu A, Stefan Kustermann S, Farinelli P, Azadi S, van Veen T, Romero FJ, Paquet-Durand F, Ekström P (2010).
Excessive HDAC activation is critical for neurodegeneration in the rd1 mouse.
Cell Death and Disease, E-published Feb 11. - Englund-Johansson U, Mohlin C, Liljekvist-Soltic I, Ekström P, Johansson K (2010).
Human neural progenitor cells promote photoreceptor survival in retinal explants.
Experimental Eye Research, 90:292-299. - Paquet-Durand F, Hauck SM, van Veen T, Ueffing M, Ekström P (2009).
PKG activity causes photoreceptor cell death in two retinitis pigmentosa models.
Journal of Neurochemistry, 108:796-810. - Sancho-Pelluz J, Arango-Gonzalez B, Kustermann S, Romero FJ, van Veen T, Zrenner E, Ekström P, Paquet-Durand F (2008).
Photoreceptor cell death mechanisms in inherited retinal degeneration.
Molecular Neurobiology, 38:253-269. - Hauck SM, Gloeckner CJ, Harley ME, Schoeffmann S, Boldt K, Ekstrom PA, Ueffing M (2008).
Identification of paracrine neuroprotective candidate proteins by a functional assay-driven proteomics approach.
Molecular and Cellular Proteomics, 7:1349-1361. - Paquet-Durand F, Johnson L, Ekström PAR (2007).
Calpain activity in retinal degeneration.
Journal of Neuroscience Research, 85:693-702. - Paquet-Durand F, Silva J, Talukdar T, Johnson LE, Azadi S, van Veen T, Ueffing M, Hauck SM, Ekström PA (2007).
Excessive activation of poly(ADP-ribose) polymerase contributes to inherited photoreceptor degeneration in the retinal degeneration 1 mouse.
Journal of Neuroscience, 27:10311-10319. - Miranda-Sanz M, Johnson L, Ahuja S, Ekström PAR, Romero JF, van Veen T. (2007).
Significant photoreceptor rescue by treatment with a combination of anti-oxidants in an animal model for retinal degeneration.
Neuroscience, 145:1120-1129. - Azadi S, Johnson L, Paquet-Durand F, Perez MTR, Zhang Y, Ekström P, van Veen T. (2007).
CNTF + BDNF treatment and neuroprotective pathways in the rd1 mouse retina.
Brain Research, 1129:116-129. - Azadi S, Paquet-Durand F, Medstrand P, van Veen T, Ekström P (2006).
Up-regulation and increased phosphorylation of protein kinase C (PKC) δ, μ and θ in the degenerating rd1 mouse retina.
Molecular and Cellular Neuroscience, 31:759-773. - Paquet-Durand F, Azadi S, Hauck SM, Ueffing M, van Veen T, Ekström P (2006).
Calpain is activated in degenerating photoreceptors in the rd1-retina.
Journal of Neurochemistry, 96:802-814. - Hauck SM1, Ekström PAR1, Ahuja-Jensen P, Suppmann S, Paquet-Durand F, van Veen T, Ueffing M (2006).
Differential modification of phosducin protein in degenerating rd1 retina is associated with constitutively active CaMKII in rod outer segments.
Molecular and Cellular Proteomics, 5:324-336. (1= shared first authorship) - Johnson L, van Veen T, Ekström PAR (2005).
Differential Akt activation in the photoreceptors of normal and rd1 mice.
Cell and Tissue Research, 320:213-222.
Research Groups
People