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Elena Prokofyeva

Current Research Projects

  • Disease onset estimation in inherited retinal dystrophies (IRD) using an epidemiological approach, comparing age of typical visual symptoms onset and clinical signs in a variety of IRD for early differential diagnosis.
  • Evaluation of quality of life perception in patients with retinitis pigmentosa.
  • The study of natural disease progression and prognosis of inherited retinal degenerations.
  • Improvement of Ophthabase, a generic extensible web-based patient registry system, with respect to design and usability as well as safety issues.
  • Comparison of prevalence and incidence rates of eye diseases in Europe, studying risk factors for eye diseases in order to enable new preventive measures.


  • Epidemiology,
  • Database studies,
  • Pharmacoepidemiology,
  • Patients related outcomes,
  • Biostatistics,
  • Public Health Informatics,
  • Literature reviews

Selected Publications

  1. Prokofyeva E, Wilke R, Lotz G, Tröger E, Strasser T, Zrenner E.
    An epidemiological approach for the estimation of disease onset in Central Europe in central and peripheral monogenic retinal dystrophies.
    Greafes Arch Clin Exp Ophthalmol 2009 Jul;247(7):885-94
  2. Tröger E, , Wilke R, ProkofyevaE, ZrennerE.
    Ophthabase: a generic extensible patient registry system.
    Acta Ophthalmologica. 2008;86(s243):0-.
  3. Tröger E, ProkofyevaE, Wilke R, ZrennerE.
    Reusability in Patient Registries - Implementation of a Generic Extensible Web-based Patient Registry System.
    HEALTHINF 2009: 438-441
  4. Prokofyeva E, Wilke R, Zrenner E. Prokofyeva E, Wilke R, Zrenner E.
    Prevalence and Incidence of Age-Related Macular Degeneration in Europe: Meta-Analysis Based on a Systematic Literature Review.
    Invest Ophthalmol Vis Sci. 2009 April 11, 2009;50(5):267-.
  5. Prokofyeva E, Wilke R, Zrenner E.
    Epidemiology of cataract in Europe. Pharmacoepidemiology and drug safety
    2009; 18: S229–S230. Published online in Wiley InterScience ( DOI: 10.1002/pds.1806
  6. Prokofyeva E, Wilke R, Zrenner E.
    Epidemiology of Diabetic Retinopathy in Europe: Meta-Analysis Based on a Systematic Literature Review.
    2009, European Congress of Epidemiology, Warsaw, Poland.
Elena Prokofyeva
Elena Prokofyeva

Research Group

Biomedical Engineering Lab


University Tübingen

Institute for Ophthalmic Research;
Biomedical Engineering Lab

Frondsbergstr. 23
72076 Tübingen

Phone: +4970712987787
Fax: +497071294472




CV of Elena Prokofyeva [pdf]

Research Groups