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Farhad Hafezi

  • Professor and Chair of Ophthalmology, University of Geneva, Switzerland
  • Clinical Professor of Ophthalmology, Doheny Eye Institute, Keck School of Medicine, University of Southern California (USC) Los Angeles, USA

Short CV

Professional Activities

2012 - present Clinical Professor of Ophthalmology, Doheny Eye Institute, Keck School of Medicine, University of Southern California (USC) Los Angeles, USA
2010 – present Professor and Chairman of Ophthalmology ("Ordinarius"), Geneva University Hospitals, Switzerland
2009 – 2011 Consultant for refractive laser surgery and corneal research, Hôpital Universitaire Ophtalmique Jules-Gonin, Lausanne
2008 "Titularprofessur", University of Zurich
2003 – 2010 Partner and shareholder of the Institute for Refractive and Ophthalmic Surgery (IROC AG), Zurich, Switzerland. An SME with currently 31 employees focused on clinical patient care and R&D in the field of ophthalmology and vision research
2002 Clinical Oculoplastic Fellow, Rotterdam Eye Clinic, Rotterdam, The Netherlands
2001 „Privatdozent“ for Ophthalmology at the University of Zurich
2000 – 2002 Staff member, Dept. of Ophthalmology, University Hospital Zurich, Switzerland
2000 Swiss Board Certification (FMH) in ophthalmology and ophthalmic surgery
1997 – 2000 Clinical residency, Dept. of Ophthalmology, University Hospital Zurich (Profs. B. Gloor and T. Seiler), Switzerland
1994 – 1997 Scientific postdoctorand, Retinal Cell Biology, Dept. of Ophthalmology, University Hospital Zurich (Prof. Charlotte E. Remé), Switzerland


2005 – 2008 PhD thesis, Dept. of Ophthalmology (Prof. Dr. med. Gabriel van Rij), Erasmus University Rotterdam, The Netherlands on "Management of Complications in Refractive Laser Surgery"
1993 – 1994 26th 2 year-postgraduate course in experimental medicine and biology (currently known as Masters in Biology), ETH and University of Zurich, Switzerland
1991 – 1992 Doctorate of Medicine, Dept. of Internal Medicine (Prof. Dr. med. Peter Weidmann), Inselspital Bern, Switzerland on "Insulin sensitivity and atrial natriuretic factor during beta-receptor modulation with celiprolol in normal subjects"

Training and Education

1986 – 1992

Medical studies in Fribourg and Berne


CV of Farhad Hafezi [pdf]

Farhad Hafezi
Farhad Hafezi


University Hospitals of Geneva

Department of Ophthalmology

22, Rue Alcide-Jentzer
CH-1211 Geneva 14

Phone: +41 (0)22 / 382 83 62
Fax: +41 / 22 - 382 84 33



Scientifc Interest

Basic research

  • Retina
    Molecular mechanisms leading to retinal degeneration. In vivo-work in transgenic animal models for retinal degeneration and ex vivo in incubated retinas. Publication of several high-impact papers.
  • Cornea
    Molecular mechanisms of corneal wound healing after refractive laser surgery. Advancing corneal collagen cross-linking technology. Keratoconus and corneal biomechanics. Scleral cross-linking.

Clinical research

  • Cornea
    Improvement of current ablation algorithms in refractive laser surgery. Establishment of new techniques for the management of complications after refractive laser surgery. Establishing the technique of corneal collagen crosslinking (CXL) for the treatment of progressive keratoconus, iatrogenic keratectasia, corneal melting processes and corneal dystrophies.


  • Association for Research in Vision and Ophthalmology (ARVO)
  • ESCRS (European Society for Cataract and Refractive Surgery)
  • EUCornea
  • AAO (American Academy of Ophthalmology)
  • SOG

Further Activities

  • Associate Editor of the Journal of Refractive Surgery
  • Editorial board member of the Iranian Journal of Ophthalmology

Key Publications

  1. Hafezi F, Steinbach JP, Marti A, Munz K, Wang ZQ, Wagner EF, Aguzzi A, Reme CE.
    The absence of c-fos prevents light-induced apoptotic cell death of photoreceptors in retinal degeneration in vivo.
    Nat Med. 1997. 3(3): 346-9
  2. Fleischmann A, Hafezi F, Elliott C, Reme CE, Ruther U, Wagner EF.
    Fra-1 replaces c-Fos-dependent functions in mice.
    Genes Dev. 2000. 14(21): 2695-700
  3. Grimm C, Wenzel A, Hafezi F, Yu S, Redmond TM, Reme CE.
    Protection of Rpe65-deficient mice identifies rhodopsin as a mediator of light-induced retinal degeneration.
    Nat Genet. 2000. 25(1): 63-6
  4. Hafezi F, Kanellopoulos J, Wiltfang R, Seiler T.
    Corneal collagen crosslinking with riboflavin and ultraviolet A to treat induced keratectasia after laser in situ keratomileusis.
    J Cataract Refract Surg. 2007. 33(12): 2035-40
  5. Iseli HP, Thiel MA, Hafezi F, Kampmeier J, Seiler T.
    Ultraviolet A/riboflavin corneal cross-linking for infectious keratitis associated with corneal melts.
    Cornea. 2008. 27(5): 590-4
  6. Hafezi F, Mrochen M, Iseli HP, Seiler T.
    Collagen crosslinking with ultraviolet-A and hypoosmolar riboflavin solution in thin corneas.
    J Cataract Refract Surg. 2009. 35(4): 621-4
  7. Hafezi F, Dejica P, Majo F.
    Modified corneal collagen crosslinking reduces corneal oedema and diurnal visual fluctuations in Fuchs dystrophy.
    Br J Ophthalmol. 2010. 94(5): 660-1
  8. Hafezi F, Koller T, Derhartunian V, Seiler T.
    Pregnancy may trigger late onset of keratectasia after LASIK.
    Journal of refractive surgery. 2012. 28(4): 242-3
  9. Richoz O, Schutz JS, Pajic B, Coskunseven E, Hafezi F.
    Crosslinking for recurrent keratoconus.
    Ophthalmology. 2012. 119(4): 878-78 e2
  10. Richoz O, Mavrakanas N, Pajic B, Hafezi F.
    Corneal Collagen Cross-Linking for Ectasia after LASIK and Photorefractive Keratectomy: Long-Term Results.
    Ophthalmology. 2013:

Research Groups