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Frank Schaeffel

Dr. Frank Schaeffel is the leader of the Section of Neurobiology of the Eye at the Institute of Ophthalmic Research, Centre for Ophthalmology, University Clinics Tuebingen, Germany.

Short CV

  • studies biology and physics, University of Freiburg
  • Dr. rer. nat. Biophysics, same place
  • Postdoc with Howard Howland Cornell University
  • Postdoc with Eberhart Zrenner Max-Planck lab Munich
  • Professor and head of Section of Neurobiology of the Eye, Ophthalmic Research Institute University of Tuebingen

Scientifc Interest

  • gene expression during myopia development
  • role of insulin and glucagon in eye growth control
  • peripheral optics of the eye
  • contrast adaptation during defocus
  • microelectrode (MEA) recordings from ganglion cells during imposed defocus


  • ARVO since 1986
  • Deutsche Zoologische Gesellschaft since 1997
  • Editorial board Vision Research since 1998
  • Editorial Board Ophthalmic and Physiological Optics since 2006
Prof. Dr. Frank Schaeffel
Prof. Dr. Frank Schaeffel

Research Group

Section of Neurobiology of the Eye
[more information]


University Clinics Tuebingen

Centre for Ophthalmology, Institute of Ophthalmic Research,
Section of Neurobiology of the Eye

Prof. Frank Schäffel
Calwerstrasse 7/1
D-72076 Tuebingen


Phone: +49-7071-2980739
Fax: +49-7071-295196


Key Publications

  • Schaeffel F.
    Binocular lens tilt and decentration measurements in healthy subjects with phakic eyes.
    Invest Ophthalmol Vis Sci. 2008 May;49(5):2216-22
  • Brand C, Schaeffel F, Feldkaemper MP.
    A microarray analysis of retinal transcripts that are controlled by image contrast in mice.
    Mol Vis. 2007 Jun 18;13:920-32
  • Schaeffel F, Mathis U, Brüggemann G.
    Noncycloplegic photorefractive screening in pre-school children with the "PowerRefractor" in a pediatric practice.
    Optom Vis Sci. 2007 Jul;84(7):630-9
  • Schippert R, Burkhardt E, Feldkaemper M, Schaeffel F.
    Relative axial myopia in Egr-1 (ZENK) knockout mice.
    Invest Ophthalmol Vis Sci. 2007 Jan;48(1):11-7
  • Diether S, Schaeffel F, Lambrou GN, Fritsch C, Trendelenburg AU.
    Effects of intravitreally and intraperitoneally injected atropine on two types of experimental myopia in chicken.
    Exp Eye Res. 2007 Feb;84(2):266-74
  • Schippert R, Schaeffel F.
    Peripheral defocus does not necessarily affect central refractive development.
    Vision Res. 2006 Oct;46(22):3935-40
  • Mathis U, Schaeffel F.
    Glucagon-related peptides in the mouse retina and the effects of deprivation of form vision.
    Graefes Arch Clin Exp Ophthalmol. 2007 Feb;245(2):267-75
  • Schaeffel F.
    Myopia: the importance of seeing fine detail.
    Curr Biol. 2006 Apr 4;16(7):R257-9
  • de la Cera EG, Rodríguez G, Llorente L, Schaeffel F, Marcos S.
    Optical aberrations in the mouse eye.
    Vision Res. 2006 Aug;46(16):2546-53

Research Groups