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The secret lymphatic identity of the Schlemm's canal

A major risk factor for glaucoma is elevated eye pressure due to poor drainage of aqueous humor, the fluid that provides nutrients to the eye.

A specialized structure, called Schlemm's canal funnels aqueous humor from the eye back into circulation. Schlemm's canal function is critical to prevent pressure build up in the eye. In this issue of the Journal of Clinical Investigation, two research groups reveal that Schlemm's canal shares features of lymphatic vessels, which maintain interstitial fluid homeostasis.