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Javier Sancho-Pelluz

Current Research Projects

Currently, my research concerns mechanisms of photoreceptor cell death during retinal degeneration. My studies are focused in different factors that can  alter gene regulation, and may lead to an enhance of cell death or survival in the photoreceptor cell layer of our animal models of retinal degeneration.

Methodology

  • Organotypic retinal explant culture
  • in vivo application, immunofluorescence and - blot
  • in situ biochemical assays

Selected Publications

  1. Sancho-Pelluz J, Wunderlich KA, Rauch U, Romero FJ, van Veen T, Limb GA, Crocker PR, Perez MT
    Sialoadhesin Expression in Intact Degenerating Retinas and Following Transplantation
    Invest Ophthalmol Vis Sci
  2. Sancho-Pelluz J, Arango-Gonzalez B, Kustermann S, Romero FJ,  van Veen T, Zrenner E, Ekström P, Paquet-Durand F
    Photoreceptor cell death mechanisms in inherited retinal degeneration
    Molecular Neurobiology 2008; accepted, in press
Javier Sancho-Pelluz
Javier Sancho-Pelluz

Research Group

Division of Experimental Ophthalmology

Contact

University of Tübingen

Centre for Ophthalmology
Institute for Ophthalmic Research

Roentgenweg 11
72076 Tuebingen
Germany

Phone: +49-7071-29-84781
Fax: +49-7071-29-5777

Email:
javier.sancho-pelluz[at]klinikum.uni-tuebingen.de

Research Groups

People

Related Research Groups

antioxidants
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apoptosis/cell death
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cell survival
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immunohistochemistry
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neuroprotection
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photoreceptors
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retina
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retinal culture
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retinal degenerations: cell biology
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retinal degenerations: hereditary
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retinitis pigmentosa
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