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Genetics and therapy of retinal blindness

Twenty researchers and technicians working on inherited retinal dystrophies and hereditary optic neuropathies. Genetics, physiopathological studies and strategy for therapies are studied. The research group is working in close collaboration with the clinical group.

Methodology

  • Molecular genetics, SNPs microarrays
  • Cell biology, gene expression and regulation
  • Protein-protein interactions

Scientific Cooperations

  • Cooperation 1:
    Bernd Wissinger, Tübingen, Germany
  • Cooperation 2:
    Shomi Bhattacharya, London, UK
  • Cooperation 3:
    Josseline Kaplan, Paris, France
  • Cooperation 4:
    Pascal Reynier, Angers, France
  • Cooperation 5:
    Gabriel Travis, Philadelphia, USA

Group Leader

Prof. Christian Hamel ✝
[more information]

Contact

INSERM U583

Institute of Neurosciences of Montpellier, Hôpital Saint Eloi

BP 74103
80, avenue Augustin Fliche
34091 Montpellier cedex 5
France

Phone: (33) 499 636 010
Fax: (33) 499 636 020

Email:
Christian.hamel[at]inserm.fr

Website:
www.inmfrance.com

Current Research Projects

  • Project 1:
    Genetics of retinitis pigmentosa and allied diseases : identification of new genes / loci, genotype/phenotype correlations
  • Project 2:
    Dominant optic atrophy : pathophysiological studies and therapeutic strategies
  • Project 3:
    Visual cycle : regulation and dysregulation in retinal dystrophies
  • Project 4:
    Gene therapy in retinal dystrophies

Research Groups

People

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gene/expression
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gene microarray
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gene transfer/gene therapy
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genetics
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retinal degenerations: hereditary
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retinal pigment epithelium
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retinitis pigmentosa
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Retinal dystrophy
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Dominant optic atrophy
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