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Retina research group

The Retina Research Group focuses in research on novel therapies and diagnostic approaches of the main retinal diseases such as age related macular degeneration, diabetic retinopathy and inherited retinal diseases.
It has both clinical and preclinical research projects and it collaborates with several groups within the University of Crete Medical School, and abroad.

In addition to the staff of the University Eye Clinic Retina Service it is also supported from the researchers of the Institute of Optics and Vision and it participates in the activities of the Postgraduate Master Program “Optics and Vision”

Methodology

  • Our projects range from preclinical animal studies to Phase 3 clinical trials.
  • In animal studies we utilize techniques such us basic light and electron, atomic force microscopy, immunohistochemistry, flow cytometry, liquid chromatography and electrophysiology in animals
  • At the same time we posses a full range of clinical diagnostic and therapeutic modalities such as digital FA, OCT, HRA, HRT, HFP, electrophysiology, access to genotyping facilities and facilities for vitreoretinal microsurgery.

Scientific Cooperations

  • Cooperation 1:
    Laboratory of Pharmacology, University of Crete Medical School
  • Cooperation 2:
    Laboratory of Toxicology, University of Crete Medical School
  • Cooperation 3:
    Department of Ophthalmology, University of Geneva, Switzerland
  • Cooperation 4:
    Department of Physics, University of Dijon, France
  • Cooperation 5:
    Department of Pharmacology, University of Patras Medical School

Group Leader

Miltiadis K. Tsilimbaris
[more information]

Contact

University of Crete Medical School

Dept. of Ophthalmology,
Institute of Optics and Vision
Voutes
Heraklion
Greece

Phone: +302810392771
Fax: +302810542094

Email:
tsilimb[at]med.uoc.gr

Current Research Projects

  • Project 1:
    Toxicity and clearance of NSAIDs after intrevitreal administration
  • Project 2:
    Utilization of flow cytometry for the differentiation of the various retinal neural cells and quantification of retinal cell apoptosis
  • Project 3:
    Evaluation of the role of Macular Pigment in wet type age-related macular degeneration
  • Project 4:
    Evaluation of the role of ocular elastic properties in posterior segment diseases
  • Project 5:
    Utilization of ultrasound enhancement agents for visualization of ocular circulation

Research Groups

People

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antioxidants
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blood supply
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ciliary body
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clinical (human) or epidemiologic studies: treatment/prevention assessment/controlled clinical trials
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diabetes
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diabetic retinopathy
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drusen
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edema
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electrophysiology: clinical
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electrophysiology: non-clinical
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endophthalmitis
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flow cytometry
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gene microarray
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genetics
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imaging/image analysis: clinical
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ischemia
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laser
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Leber congenital amaurosis
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macula/fovea
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macular dystrophy, inherited
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macular holes
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macular pigment
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microscopy: confocal/tunneling
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neovascularization
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neuropeptides
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neuroprotection
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photodynamic therapy
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photoreceptors
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quality of life
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retina
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retina: distal (photoreceptors, horizontal cells, bipolar cells)
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retina: neurochemistry
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retina: proximal (bipolar, amacrine, and ganglion cells)
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retinal adhesion
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retinal connections, networks, circuitry
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retinal culture
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retinal degenerations: cell biology
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retinal degenerations: hereditary
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retinal detachment
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retinal development
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retinal glia
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retinal neovascularization
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retinal pigment epithelium
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retinitis
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retinitis pigmentosa
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retinochoroiditis
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vitreoretinal surgery
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vitreoretinopathies
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vitreous
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vitreous substitutes
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vitreoretinal
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intravitreal
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apoptosis
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neuroprotection
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ocular rigidity
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