You are here: vision-research.eu » People » Research Groups » United Kingdom » Hindges, Robert

Visual mapping and circuits group

We are interested in the molecular control of the development and maintenance of visual circuits. One focus is the establishment of a retinotopic map and the segregation of ipsi- and contralateral projections at the midline to form binocular vision.

In addition, we aim to understand the role of molecules (proteins and RNAs) in the generation of retinal cell subtypes and their specific connectivity. We use mainly the mouse and chick as model systems for our studies on visual development in healthy and diseased states.

Methodology

  • Generation/use of transgenic and gene-targeted mouse lines
  • Genetic- and dye-based in vivo tracing of retinal axons, 2P/confocal microscopy
  • In utero (mouse) and in ovo (chick) electroporations in retina and visual targets

Scientific Cooperations

  • Visual systems group at KCL (Prof. Uwe Drescher, Prof. Ian Thompson, Dr. Martin Meyer)
  • Dr. Juan Burrone, KCL
  • Dr. Kevin Mitchell, University of Dublin
  • Prof. Anne Calof, UC Irvine

Group Leader

Robert Hindges
[more information]

Contact

King’s College London

MRC Centre for Developmental Neurobiology

New Hunt’s House
Guy’s Campus
SE1 1UL London
United Kongdom

Phone: +44 (0)20 7848 8157
Fax: +44 (0)20 7848 6550

Email:
robert.hindges[at]kcl.ac.uk

Website:
Visual mapping and circuits group

Current Research Projects

  • Role of miRNAs in retinal development and axon pathfinding
  • Establishment of the visual topographic map
  • Molecular basis of binocular vision
  • Subtype-specific interactions/synaptogenesis of cells in the retina and retinorecipient structures in the brain
  • Molecular markers of specific retinal circuits

Research Groups

People

Related Research Groups

binocular vision/stereopsis
Oops, an error occurred! Code: 202003311534246ce89078
ganglion cells
Oops, an error occurred! Code: 202003311534248934fbe2
gene microarray
Oops, an error occurred! Code: 20200331153424d519db60
retinal development
Oops, an error occurred! Code: 2020033115342445e75c4c
superior colliculus/optic tectum
Oops, an error occurred! Code: 20200331153424752f3acd
thalamus/lateral geniculate nucleus
Oops, an error occurred! Code: 20200331153424363e5f54
topography
Oops, an error occurred! Code: 20200331153424bceffcfe
transgenics/knock-outs
Oops, an error occurred! Code: 20200331153424894bae22
visual development
Oops, an error occurred! Code: 20200331153424fef54934
retinotopic map
Oops, an error occurred! Code: 20200331153424f6ad0976
microRNAs
Oops, an error occurred! Code: 20200331153424b2c9592b
retinal degeneration
Oops, an error occurred! Code: 20200331153424b365aa09
binocular vision
Oops, an error occurred! Code: 20200331153424c8db727a
intraretinal connectivity
Oops, an error occurred! Code: 20200331153424398a5b30