You are here: vision-research.eu » People » Research Groups » Germany » Paulsen, Friedrich

Tear film, ocular surface and dry eye

Our group is mainly interested in the function of proteins and peptides that influence tear film peptides (beta defensins, proriasin, and other), surfactant proteins and also hormones such as somatostatin or relaxin.

Moreover, we try to understand physiologic and pathophysiolic mechanisms of cornea, conjunctiva, lacrimal gland, accessory lacrimal glands, Meibomian glands, lid margin, lids, and nasolacrimal ducts. Finally, major focus is on lacrimal gland reconstruction and lacrimal gland stem cell research.

Methodology

  • Cell culture,
  • cell lines (cornea, conjunctiva, meibocytes),
  • dry eye model (mice),
  • cornea wound healing models,
  • immunogold electron microscopy,
  • cell biology,
  • molecular biology

Group Leader

Friedrich Paulsen
[more information]

Contact

Friedrich-Alexander-University Erlangen-Nuremberg

Department of Anatomy II

Universitätsstr. 19
91054 Erlangen
Germany

Phone: +49 91318522865
Fax: +49 91318522862

E-mail:
friedrich.paulsen[at]anatomie2.med.uni-erlangen.de

Website:
www.anatomie2.med.uni-erlangen.de

Scientific Cooperations

  • Cooperation 1
    Yolanda Diebold, IOBA, Valladolid, Spain
  • Cooperation 2
    Thomas Millar, School of Natural Sciences, University of Sydney, Australia
  • Cooperation 3
    Robert Sack, College of Opthometry, SUNY, NY, USA
  • Cooperation 4
    Monica Berry, School of Clinical Sciences, University of Bristol, UK
  • Cooperation 5
    Stephan Mergler, Group leader ophthalmology research lab, Charité, Berlin, Germany

Current Research Projects

  • Project 1
    Detection and function of antimicrobial peptides in the tear film
  • Project 2
    Proteins of meibomian glands
  • Project 3
    Regulation of meibomian gland secretion
  • Project 4
    Stem cells of lacrimal gland
  • Project 5
    Function of surfactant proteins in the tear film

Research Groups

People

Related Research Groups

aqueous
Oops, an error occurred! Code: 20181217014352cc1f2c36
conjunctiva
Oops, an error occurred! Code: 20181217014352e68994a1
cornea: basic science
Oops, an error occurred! Code: 2018121701435270c577d3
cornea: epithelium
Oops, an error occurred! Code: 201812170143520cf8fb87
cornea: surface mucins
Oops, an error occurred! Code: 20181217014352c873d650
cornea: tears/tear film/dry eye
Oops, an error occurred! Code: 2018121701435268973d34
lacrimal gland
Oops, an error occurred! Code: 20181217014352a02857f6
microbial pathogenesis: experimental studies
Oops, an error occurred! Code: 2018121701435204949e9d
wound healing
Oops, an error occurred! Code: 2018121701435274345a23
lacrimal gland
Oops, an error occurred! Code: 201812170143521a7020fa
tear film
Oops, an error occurred! Code: 20181217014352ec639c59
tears
Oops, an error occurred! Code: 20181217014352b61dd990
Meibomian gland
Oops, an error occurred! Code: 2018121701435223d74303