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Experimental and Translational Ophthalmology

Our main interests include glaucoma, tear film, neuroprotection, proteomics, and bioinformatics.

As a part of the Dept. of Ophthalmology, we are attempting to close the gap between clinical and basic sciences. We perform both clinical trials and basic science research using state of the art technology for proteomic research using mass spectrometry and micro-array technology. Additionally, results for proteomic research are further complemented by analysis in animal models and cell culture experiments.


  • conventional electrophoretic systems and microarray technology, as well as mass spectrometry laboratory, cell culture, animal facility,  immunohistochemistry and microscopy

Group Leader

Franz Grus
[more information]


Johannes Gutenberg University

University Medical Center
Eye Clinic
Experimental and Translational Ophthalmology

Langenbeckstr. 1
55131 Mainz

Phone: +49-6131 173328



Scientific Cooperations

  • Cooperation 1:
    Gutenberg Health Study, Mainz, Germany
  • Cooperation 2:
    EU- FP7 project: STRONG study
  • Cooperation 3:
    Novartis Pharma AG
  • Cooperation 4:
    Prof. Jonathan Crowston
    Head of the Department of Ophthalmology at the University of Melbourne and Managing Director Centre for Eye Research Australia/ MELBOURNE 
  • Cooperation 5:
    Professor Paulsen, Erlangen, Germany

Current Research Projects

  • Project 1
    European Consortium for the Study of a topical Treatment of Neovascular Glaucoma- the STRONG Study:
  • Project 2
    Autoantibodies in Glaucoma: importance for early diagnosis and therapy
  • Project 3
    Prognostic Relevance of Antibodies and further Determination of Antibody Profiles Against retinal Antigenes in AMD
  • Project 4
    Analysis of protective effects of antibodies on neuroretinal cells
  • Project 5
    Anti-angionetic Effects of Antibodies in a Laser induced choroidal neovascularization AMD animal model

Research Groups