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Experimental and Translational Ophthalmology

Our main interests include glaucoma, tear film, neuroprotection, proteomics, and bioinformatics.

As a part of the Dept. of Ophthalmology, we are attempting to close the gap between clinical and basic sciences. We perform both clinical trials and basic science research using state of the art technology for proteomic research using mass spectrometry and micro-array technology. Additionally, results for proteomic research are further complemented by analysis in animal models and cell culture experiments.

Methodology

conventional electrophoretic systems and microarray technology, as well as mass spectrometry laboratory, cell culture, animal facility, immunohistochemistry and microscopy

Group Leader

Franz Grus
[more information]

Contact

Johannes Gutenberg University

University Medical Center
Eye Clinic
Experimental and Translational Ophthalmology

Langenbeckstr. 1
55131 Mainz
Germany

Phone: +49-6131 173328

E-mail:
grus[at]eye-research.org

Website:
www.eye-research.org

Scientific Cooperations

Cooperation 1:
Gutenberg Health Study, Mainz, Germany
Cooperation 2:
EU- FP7 project: STRONG study
Cooperation 3:
Novartis Pharma AG
Cooperation 4:
Prof. Jonathan Crowston
Head of the Department of Ophthalmology at the University of Melbourne and Managing Director Centre for Eye Research Australia/ MELBOURNE
Cooperation 5:
Professor Paulsen, Erlangen, Germany

Current Research Projects

Project 1
European Consortium for the Study of a topical Treatment of Neovascular Glaucoma- the STRONG Study:
Project 2
Autoantibodies in Glaucoma: importance for early diagnosis and therapy
Project 3
Prognostic Relevance of Antibodies and further Determination of Antibody Profiles Against retinal Antigenes in AMD
Project 4
Analysis of protective effects of antibodies on neuroretinal cells
Project 5
Anti-angionetic Effects of Antibodies in a Laser induced choroidal neovascularization AMD animal model