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Olaf Strauss


Short CV

1983-88 Studies Biology Diploma Free University Berlin
1990 PhD at the Institute of Clinical Physiology Free University Berlin
1998 Habilitation in Physiology, Free University Berlin
2002-2007 Professor Experimental Ophthalmology at the Eye Hospital, University Hospital Hamburg-Eppendorf
  Professor Experimental Ophthalmology Eye-Hospital, University Hospital Regensburg

Documents

CV of Olaf Strauss [pdf]

Scientifc Interest

Since 1990 Olaf Strauss is investigating the function and the regulation of function of the retinal pigment epithelium in health and disease.  In focus are ion channels and their regulation and how the activity of these ion channels is involved the regulation of cell function.
From this base he broadened the spectrum to the analysis of extracellular and intracellular signalling involving growth-factors, intracellular Ca2+and analysis of the protein/protein interaction underlying these key-events.

Memberships

  • Association for Research in Vision and Ophthalmology (ARVO)
  • Am. Physiological Society
  • International Society of Eye Research (ISER)
  • German Physiological Society
Olaf Strauss
Olaf Strauss

Research Group

Experimentelle Ophthamologie Regensburg

Contact

Klinik und Polklinik für Augenheilkunde
Klinikum der Universität Regensburg

Franz-Josef-Strauss Allee 11
93053 Regensburg
Germany

Phone: +49-941-9228
Fax: +49-941-9202

Email:
strauss[at]eye-regensburg.de

Website:
Experimentelle Ophthamologie Regensburg

Key Publications

  1. Strauß, O., Mergler, S., Wiederholt, M. (1997).
    Regulation of L-type calcium channels by protein tyrosine kinase and protein kinase C in cultured rat and human retinal pigment epithelial cells.
    FASEB J. 11, 859-67.
  2. Strauß, O., Buss, F., Rosenthal, R., Fischer, D., Mergler S., Stumpff F., Thieme H. (2000).
    Activation of neuroendocrine L-type channels (1D subunits) in retinal pigment epithelial cells and brain neurons by pp60c-src.
    Biochem. Biophys. Res. Commun. 270, 806-10.
  3. Rosenthal, R., Thieme, H., Strauß, O. (2001).
    Fibroblast growth receptor 2 (FGFR2) in brain neurons and retinal pigment epithelial cells act via stimulation of neuroendocrine L-type channels (Cav1.3).
    FASEB J. 15, 970-7.
  4. Strauß, O., Rosenthal, R., Dey, D., Beninde, J., Wollmann, G., Thieme, H., Wiederholt, M. (2002).
    Effects of protein kinase C delayed rectifier K+ channel regulation by tyrosine kinase in rat retinal pigment epithelial cells.
    Invest. Ophthalmol. Vis. Sci. 43, 1645-54.
  5. Fidzinski, P., Knoll, A., Rosenthal, R., Schrey, A., Vescovi, A, Koert U., Wiederholt M., Strauß, O. (2003).
    Electrophysiological response of cultured trabecular meshwork cells to synthetic ion channels.
    Chem. Biol. 10, 35-43.
  6. Rosenthal, R., Wohlleben, H., Malek, G., Schlichting, L., Thieme, H., Bowes Rickman, C., Strauß, O. (2004).
    Insulin-like growth factor-1 contributes to neovascularization in age-related macular degeneration.
    Biochem. Biophys. Res. Commun. 323, 1203-8.
  7. Wollmann, G., Lenzner, S., Berger, W., Rosenthal, R., Karl, M.O., Strauß, O. (2006).
    Voltage-dependent ion channels in the mouse RPE: comparison with Norrie disease mice.
    Vision Res. 46, 688-98.
  8. Rosenthal, R., Bakall, B., Kinnick, T., Peachey, N., Wimmers, S., Wadelius, C., Marmorstein, A., Strauß, O. (2006).
    Expression of bestrophin-1, the product of the VMD2 gene, modulates voltage-dependent Ca2+ channels in retinal pigment epithelial cells.
    FASEB J. 20, 178-80.
  9. Strauß, O. (2005).
    The retinal pigment epithelium in visual function.
    Physiol. Rev. 85, 845-81.
  10. Karl MO, Kroeger W, Wimmers S, Milenkovic VM, Valtink M, Engelmann K, Strauss O (2008)
    Endogenous Gas6 and Ca2+-channel activation modulate phagocytosis by retinal pigment epithelium.
    Cell Signal Feb 16: e-pub ahead of print.

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