You are here: vision-research.eu » Vision Research » Vision in the European Focus » Vision in the European Focus - Details
The ‘Publication of the Year’ reflects the personal choice and preference of the community submitted by its members. This year again we had a tremendous feedback and received suggestions from all over the world. We are very happy about these results and the enthusiasm of the community.
Author/s | Cowan CS, Renner M, De Gennaro M, Gross-Scherf B, Goldblum D, Hou Y, Munz M, Rodrigues TM, Krol J, Szikra T, Cuttat R, Waldt A, Papasaikas P, Diggelmann R, Patino-Alvarez CP, Galliker P, Spirig SE, Pavlinic D, Gerber-Hollbach N, Schuierer S, Srdanovic A, Balogh M, Panero R, Kusnyerik A, Szabo A, Stadler MB, Orgül S, Picelli S, Hasler PW, Hierlemann A, Scholl HPN, Roma G, Nigsch F, Roska B. |
---|---|
Journal | Cell. 2020 Sep 17;182(6):1623-1640.e34. doi: 10.1016/j.cell.2020.08.013. PMID: 32946783 |
Comment | This paper is a seminal resource for future work in characterization and treatment of eye diseases. |
Author/s | Sybille Böhm, Victoria Splith, Lisa Maria Riedmayr, René Dominik Rötzer, Gilles Gasparoni, Karl J V Nordström, Johanna Elisabeth Wagner, Klara Sonnie Hinrichsmeyer, Jörn Walter, Christian Wahl-Schott, Stefanie Fenske, Martin Biel, Stylianos Michalakis, Elvir Becirovic |
---|---|
Journal | Sci Adv 2020 Aug 19;6(34):eaba5614. doi: 10.1126/sciadv.aba5614. eCollection 2020 Aug. doi: 10.1126/sciadv.aba5614 |
Comment | This is the first in vivo proof-of-concept study for a novel gene therapy principle of "trans-activation" of a functionally equivalent gene to restore a missing gene function and provide a therapeutic benefit in inherited retinal disorders. |
Author/s | Dasha Nelidova 1 2, Rei K Morikawa 1 2, Cameron S Cowan 1 2, Zoltan Raics 1 2, David Goldblum 3, Hendrik P N Scholl 1 3 4, Tamas Szikra 1 2, Arnold Szabo 5, Daniel Hillier 6 2 7 8 9, Botond Roska 6 2 3 |
---|---|
Journal | Science. 2020 Jun 5;368(6495):1108-1113. doi: 10.1126/science.aaz5887. |
Comment | Enabling near-infrared light sensitivity in a blind human retina may supplement or restore visual function in patients with regional retinal degeneration. |
Author/s | Chi Zhang 1, Yeon Jin Kim 1, Ana R Silverstein 1, Akina Hoshino 1, Thomas A Reh 1, Dennis M Dacey 2, Rachel O Wong 3 |
---|---|
Journal | Neuron 2020 Dec 9;108(5):905-918.e3. doi: 10.1016/j.neuron.2020.09.014. Epub 2020 Oct 6. |
Comment | The human visual pathway is specialized for the perception of fine spatial detail. The neural circuitry that determines visual acuity begins in the retinal fovea, where the resolution afforded by a dense array of cone photoreceptors is preserved in the retinal output by a remarkable non-divergent circuit: cone → midget bipolar interneuron → midget ganglion cell (the "private line"). |
Author/s | Susanne Wiemann 1, Jacqueline Reinhard 1, Sabrina Reinehr 2, Zülal Cibir 1, Stephanie C Joachim 2, Andreas Faissner 1 |
---|---|
Journal | Front Immunol 2020 Oct 9;11:566279. doi: 10.3389/fimmu.2020.566279. eCollection 2020. |
Comment | The fascinating point in this story is that loss of an extracellular matrix protein can lead to drastic changes in the immune response. This story can also teach us more about the positive and even negative features of proteins that persist or that are re-expressed after being essentially useful during embryonic development. |
Author/s | Saad Idrees 1, Matthias P Baumann 1 2, Felix Franke 3, Thomas A Münch 4 5, Ziad M Hafed 6 7 |
---|---|
Journal | Nat Commun 2020 Apr 24;11(1):1977. doi: 10.1038/s41467-020-15890-w. |
Comment | Demonstrates a retinal origin for a robust and well-known perceptual phenomenon in humans around the time of saccadic eye movements. Also allows recasting the role of extra-retinal mechanisms in the same phenomenon. |
Author/s | Paul-Henri Prévot 1, Kevin Gehere 1, Fabrice Arcizet 1, Himanshu Akolkar 1, Mina A Khoei 1, Kévin Blaize 1, Omar Oubari 1, Pierre Daye 1, Marion Lanoë 1, Manon Valet 1, Sami Dalouz 1, Paul Langlois 1, Elric Esposito 1, Valérie Forster 1, Elisabeth Dubus 1, Nicolas Wattiez 2, Elena Brazhnikova 1, Céline Nouvel-Jaillard 1, Yannick LeMer 3, Joanna Demilly 4, Claire-Maëlle Fovet 4, Philippe Hantraye 4, Morgane Weissenburger 2, Henri Lorach 5, Elodie Bouillet 6, Martin Deterre 6, Ralf Hornig 6, Guillaume Buc 6, José-Alain Sahel 1 3 7 8, Guillaume Chenegros 1, Pierre Pouget # 2, Ryad Benosman # 1 7, Serge Picaud # 9 |
---|---|
Journal | Nat Biomed Eng 2020 Feb;4(2):172-180. doi: 10.1038/s41551-019-0484-2. Epub 2019 Dec 2. |
Comment | A study on non human primate validating perception with a retinal prosthesis prior to a clinical trial |
Author/s | Yvonne Kölsch 1, Joshua Hahn 2, Anna Sappington 3, Manuel Stemmer 4, António M Fernandes 4, Thomas O Helmbrecht 4, Shriya Lele 4, Salwan Butrus 2, Eva Laurell 4, Irene Arnold-Ammer 4, Karthik Shekhar 5, Joshua R Sanes 6, Herwig Baier 7 |
---|---|
Journal | Neuron 2021 Feb 17;109(4):645-662.e9. doi: 10.1016/j.neuron.2020.12.003. Epub 2020 Dec 23. |
Comment | - Transcriptional profiling classifies >30 distinct retinal ganglion cell types - Molecular profiles of RGCs correlate with morphological and physiological features - Genome-engineered driver lines provide selective access to RGC types - Perturbation of a genetically defined visual pathway disrupts phototaxis |
Author/s | Jacqueline Reinhard 1, Natalie Wagner 1, Miriam M Krämer 1, Marvin Jarocki 1, Stephanie C Joachim 2, H Burkhard Dick 2, Andreas Faissner 1, Vinodh Kakkassery 2 3 |
---|---|
Journal | Int J Mol Sci 2020 Jun 17;21(12):4322. doi: 10.3390/ijms21124322. |
Comment | The article contributes to a better understanding of the role of the extracellular matrix in the therapy resistance of retinoblastoma. |
Author/s | Nicolás Cuenca 1, Isabel Ortuño-Lizarán 2, Xavier Sánchez-Sáez 2, Oksana Kutsyr 2, Henar Albertos-Arranz 2, Laura Fernández-Sánchez 3, Natalia Martínez-Gil 2, Agustina Noailles 2, José Antonio López-Garrido 4, Maribel López-Gálvez 5, Pedro Lax 2, Victoria Maneu 3, Isabel Pinilla 6 |
---|---|
Journal | Prog Retin Eye Res 2020 Jul;77:100828. doi: 10.1016/j.preteyeres.2019.100828. Epub 2020 Jan 3. |
Comment | An overview of how to interpret the OCT and OCTA images from the histological point of view and discuss important aspects regarding the clinical implications and experimental evaluations. New unpublished data are presented, to compare the histological pictures, obtained using immunohistochemistry, with OCT and OCTA images in human and animal models of retinal degeneration. |
Our congratulation goes to all winners and we may thank all contributors for their constructive submissions.
We are looking forward for the best puplications in 2021.