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04/27/17

Research Scientist at the Veneto Eye Bank Foundation, Italy

The Veneto Eye Bank Foundation (FBOV, www.fbov.org and http://research.fbov.org/) is one of the leading eye banks in Europe. The Research Centre of FBOV employees scientists involved in pre-clinical and clinical research focused on corneal cell biology, vision science, and corneal transplantation.

FBOV is seeking a highly motivated Research Scientist who will contribute to the development of (I) new tissue culture media for storage of human corneas, (II) surgical solutions and devices for corneal transplantation, and (III) protocols for culturing and characterizing corneal endothelial cells, either from progenitor or induced stem cells.

The ideal candidate should have the following qualifications:

  • a Bachelor Degree in Biology/Biotechnology with a few years of industrial/academic experience or PhD in a relevant scientific discipline (Biology, Molecular Biology, Biochemistry, Pharmaceutical Sciences);
  • be fluent in English;
  • technical proficiency in the following areas: cell and tissue culture, immunohistochemistry, microscopy (confocal is a great plus), molecular biology;
  • a previous experience in an eye bank or in projects/studies involving the cornea would be an advantage;
  • keen on writing papers, and presenting results at national/international conferences and networking with Italian/European colleagues.

The candidate will be required to interact closely and positively with other research scientists, eye bank technicians, ophthalmologists and surgeons.

The position is available immediately for 2 years in the first instance, although continuation may be possible. Workplace will be based in the Research Centre of the Veneto Eye Bank Foundation in mainland Venice (Italy) next to newly built “Dell’Angelo Hospital”. Salary (first year €20,000 – €25,000) will be commensurate with skills and experience.

Candidates from the European Union are strongly encouraged to apply.

All applicants must be able to demonstrate the right to live and work in Italy in order to be considered. Application is by CV and covering letter and should be sent to Dr Stefano Ferrari by email (stefano.ferrari[at]fbov.it).

Contact details:

Stefano Ferrari, PhD
Fondazione Banca degli Occhi del Veneto
30174 Zelarino (Venezia) - ITALY

Email: stefano.ferrari[at]fbov.it
www.fbov.org

04/07/17

Postdoctoral Scientist in Protein Network Analysis for Age-related Macular Degeneration

The lab of Prof. Marius Ueffing at the Institute for Ophthalmic Research, University of Tübingen, Germany, is looking for a

Postdoctoral Scientist in Protein Network Analysis for Age-related Macular Degeneration

The Ueffing lab is applying systems medicine approaches to retinal degeneration. The lab runs a state-of-the-art facility for mass spectrometric analysis of proteins and metabolites. Within the EYE-RISK consortium the group collaborates with research institutions, eye clinics and industry to investigate the molecular drivers and risks of Age-related macular degeneration (AMD), Europe’s most frequent cause for blindness. EYE-RISK applies new methods in genetics, biochemistry and bioinformatics to build a robust and validated model of AMD pathways and risks. For insight into our methods and approaches see Boldt et al. 2016, Körtvely et al. 2016, Sacco et al. 2014, Kiel et al. 2011, Kiel et al. 2017.

Your tasks:

  • assembling the map of protein complexes and interactions in AMD
  • validating computational simulations of disease pathways by proteomics and cell biology (cf. Boldt et al. Nat Comm. 2016 for methods)
  • analysing biochemical properties of proteins coded by AMD risk variants (cf. Körtvely et al. Hum Mol Genet. 2016 for methods)
  • validating risk algorithms by analysing patient samples

Your profile:

  • background in proteomics, biochemistry or molecular biology
  • creativity & team spirit
  • experience in vision science, neurobiology, molecular genetics or protein science
  • talents in method development
  • decent publication record

We offer an environment for advanced research and close interaction with scientists in the lab and associated laboratories. You will work - in the systems medicine consortium EYE-RISK including leading European investigators, - in advanced analysis of the largest AMD patient cohorts in Europe, - within one of the leading Centers for Ophthalmology in Europe, - in a large and diverse lab firmly embedded into the neuroscience community on campus, - using the full spectrum of –omics technologies including SRM, phosphoproteomics, lipidomics, metabolomics, transcriptomics, RNAseq, and you can receive a competitive salary (according to your experience and within the legal framework of employment laws).

The position is available from the earliest date possible, initially limited to the duration of the EYE-RISK project until 30.04.2019, with plans for a further extension.

We offer remuneration in accordance with TV-L (collective wage agreement for the Public Service of the German Federal state) in addition to all the customary benefits granted to employees working in Public services. Severely handicapped persons with equal qualifications are given preferential consideration. The University of Tübingen is anxious to increase its quota of female scientific staff, and herefore emphatically requests women to apply for this position. The Administration of the University Hospital is responsible for all employment matters. Personnel appointments will be made pursuant to the fundamental stipulations of the legal statutes for universities in Germany.

Please include your cover letter, CV and the names of three academic references into a single pdf file and send your application to ellen.kilger[at]uni-tuebingen.de.

PhD and Postdoc positions in Sensory/Systems Neuroscience

In January 2017, our collaborative research centre “Robust Vision – Inference Principles and Neural Mechanisms” (CRC 1233) started. Funded by the DFG (German Research Foundation), a group of more than 20 PIs will jointly address the question why biological visual systems are so remarkably robust. To this end, we will combine expertise in experimental and computational neuroscience, as well as in machine learning and computer vision.

As part of interdisciplinary collaborations within the CRC, 6 PhD and 1 Postdoc positions are available in different labs at the University of Tübingen.

Positions

1) One PhD student position

Applications are sought for one PhD student position on the topic of “Natural stimuli for mice: environment statistics and neural representations in the early visual system” in the group of Thomas Euler at the Institute for Ophthalmic Research and the Centre for Integrative Neuroscience (CIN).

This project will explore the visual input received by the mouse visual system under natural conditions and how such input is processed along key stages of the early visual system. We expect a better understanding of efficient neural coding of natural scenes and the extent to which early visual representations are adapted to the statistics of the visual world. The PhD student will be responsible for the acquisition of natural movies, and for in vitro two-photon calcium recordings from the mouse retina. The project will be jointly conducted with a PhD student who will be based primarily in Laura Busse’s lab at the LMU Munich and will focus on in vivo recording from mouse primary visual cortex in response to naturalistic stimuli.

The candidate for the position in Tübingen requires strong engineering skills, a keen interest in neural computations and the readiness to acquire the necessary experimental skills. A background in neuroscience will be considered an asset. Importantly, the candidate requires the ability to work in a distributed team. 

The candidate will be working at the CIN and the Institute for Ophthalmic Research under the joint supervision of Frank Schaeffel and Thomas Euler, in close collaboration with the Zeiss Vision Science Lab and Laura Busse’s group at the LMU Munich.

Applications should include a CV, a statement of research motivation and experience, and the names of at least two referees. Please compile your application in one single PDF-file and email it to positions[at]eulerlab.org. See also “General Information” below.

2) Two PhD student positions

Applications are sought for two PhD student positions on the topic of “Image processing within a locally complete retinal ganglion cell population”. One position will focus on the experimental and data analysis part in the group of Thomas Euler at the Institute for Ophthalmic Research and the Centre for Integrative Neuroscience (CIN). The other position will focus on the theoretical and computational modelling part in the group of Matthias Bethge at the CIN.

The goal of this project is to build data-driven convolutional neural network models as well as theory-driven models that capture the specific nonlinear computations performed by neural circuits in the retina of the mouse. The project will be jointly conducted by the two PhD students. Both students are expected to contribute to data analyses and model evaluation.

The candidate for the position in the Euler lab requires experimental skills, and a keen interest in neural computations and the visual system. The PhD student will be responsible for the experimental side including data analysis, providing for the collection of large amounts of two-photon data on which data-driven model development relies. In addition, the PhD student is expected to contribute to model evaluation. Therefore, this position will include opportunities for designing a broad set of visual stimuli, and for in vitro two-photon calcium recordings from the mouse retina. A background in theoretical neuroscience will be considered an asset.

The candidate for the PhD position in the Bethge lab requires a strong background in Machine Learning and interest in neuroscience. Experience with deep learning and deep learning software such as TensorFlow will be particularly useful. More generally, expertise in system identification, optimization, and cross-validation will be important to the project. Besides the CRC, the position will provide great opportunities to interact with an international team of researchers working on related projects in the visual cortex.

The candidates will be working at the Institute for Ophthalmic Research, the CIN, and the Bernstein Centre for Computational Neuroscience (BCCN) under the joint supervision of Matthias Bethge and Thomas Euler, in close collaboration with Philipp Berens.

Applications should include a CV, a statement of research motivation and experience, and the names of at least two referees. Please compile your application in one single PDF-file and email it to positions@eulerlab.org for the experimental position and to applications[at]bethgelab.org for the theoretical position. See also “General Information” below.

3) One PhD position

One PhD position is available in the group of Philipp Berens at the Institute for Ophthalmic Research and the Center for Integrative Neuroscience (CIN) of the University of Tübingen.

In collaboration with Laura Busse (LGN/V1 physiology, LMU Munich) and Thomas Euler (retinal
imaging, University of Tübingen), the project will investigate transformations of representations between the retina and the dorsolateral geniculate nucleus (dLGN) of the thalamus.

The student in the Berens lab will be responsible for data analysis and development of new models of neural processing in the retina and LGN. The project requires strong analytical skills and programming experience ideally in Python/R; a background in computational neuroscience or machine learning is considered a plus. A second PhD student based primarily in Munich will have an experimental focus.  Because of the interdisciplinary nature of the project, excellent collaboration and team skills are essential.

Applications should include a CV, a statement of research motivation and experience, and the names of at least two referees. Please compile your application in one single PDF-file and email it to philipp.berens[at]uni-tuebingen.de and add [CRC PhD Student] in the title. See also “General Information” below.

4) One PhD position

One PhD position is available in the lab of Frank Schaeffel at the Ophthalmic Research Institute. The project studies perceptual consequences  of fixational eye movements and will be jointly supervised by Frank Schaeffel, Ziad Hafed at the CIN and Katharina Rifai at the Zeiss Vision Lab. Profile of expertise is neurophysiology, vision, physiological  optics, human psychophysics, C++ programming (or at least strong interest in learning it). We are looking for a biologist, psychologist, or someone from related fields. Eligibility  for the PhD program is mandatory (a Master degree or equivalent).

Applications should include a statement of interest, CV, certificates documenting scientific training, two names for references, and a publication list. Please compile your application in one single PDF file and e-mail it to frank.schaeffel[at]uni-tuebingen.de. See also “General Information” below.

5) One Postdoc position

One Postdoc position is available in the lab of Ziad Hafed at the CIN. The research project represents a neurophysiological analysis of the visual consequences of fixational eye movements, using non-human primate neurophysiology and will be jointly supervised by Ziad Hafed, Frank Schaeffel and Katharina Rifai. The profile of expected expertise includes visual system,  neurophysiology, C++ and/or MatLab programming (or at least strong interest in learning it). Experience with non-human primate neurophysiology is not mandatory (will be learned in the lab), but will be highly valued. We are looking for a biologist, psychologist, or somebody from related fields. Completed requirements for a PhD are mandatory.

Applications should include a statement of interest, CV, certificates documenting scientific training, two names for references, and a publication list. Please compile your application in one single PDF file and e-mail it to ziad.m.hafed[at]cin.uni-tuebingen.de. See also “General Information” below.

6) One PhD position

One PhD position is available in the group of Günther Zeck at the Natural and Medical Sciences Institute (NMI) at the University of Tübingen.
In collaboration with Jakob Macke (caesar Bonn) , Katharina Stingl and Eberhart Zrenner (Ophthalmic Research Institute, University of Tübingen), the project “Image-processing computations in artificial vision“ will investigate how electrically stimulated blind retina will achieve robust object coding. The PhD student will be responsible for electrical stimulation and for extracellular recording from blind mouse retina using micro-electrode arrays. Together with the collaboration partners, algorithms for robust object identification will be developed and tested with blind patients.

The project requires skills in neural engineering, interest in neural computations and the readiness to acquire the necessary experimental skills. Because of the interdisciplinary nature of the project, excellent collaboration and team skills are essential.

Applications should include a CV, a statement of research motivation and experience, and the names of two referees. Please compile your application in one single PDF-file and email it to guenther.zeck[at]nmi.de  and add [CRC PhD Student] in the title. See also “General Information” below.

General information

For the PhD position applications, eligibility for the PhD program is mandatory (a MSc degree or equivalent). Positions are immediately available, with funding for 3 years (with the option on a 1-year extension). We offer employment with a salary and social benefits based on the collective agreement for public service employees in the academic and science sector, TV-L. The CRC promotes gender equality and therefore particularly encourages female scientists to apply. Preferential status will be given to handicapped persons, if equally qualified.

The Werner Reichardt Centre for Integrative Neuroscience (CIN) is an interdisciplinary institution funded by the German Excellence Initiative program. The CIN strives to deepen our understanding of how the brain generates function and how brain diseases impair functions. Its scientific program is guided by the conviction that progress in the understanding of brain function can be achieved with an integrative approach spanning multiple levels of organization and pooling the knowledge of researchers from many different fields.

The Institute for Ophthalmic Research cooperates closely with the University Eye Hospital under the umbrella of the Centre for Ophthalmology. The Institute aims at uncovering the causes for degenerative, inflammatory, neoplastic, and vascular diseases of the eye and developing diagnostics and therapies based on these discoveries. Translational research is jointly performed with the University Eye Hospital Tuebingen.

The Natural and Medical Sciences Institute (NMI) at the University Tübingen conducts application-oriented research at the interface between the life sciences and material science. Together with scientific and industrial partners the NMI facilitates the successful launching of numerous products into the biomedical market.

Tübingen is a vibrant university city in the south of Germany. Besides the CIN, Tübingen is also home to the Hertie Institute for Cognitive Neurology and several institutes of the Max Planck Society, among others. This allows for a tremendous exposure to the latest advances in neuroscience, vision/robotics, human-computer interaction, brain-computer interfaces, etc. There are also opportunities for collaborative projects across labs/institutes.

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