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A new Lancet Series focuses on increasing value and reducing waste in research

The Series documents waste in research from five principal sources — ranging from waste in deciding what research to do, through to waste because of unusable reports of research.

The Lancet presents a Series of five papers about research. In the first report Iain Chalmers et al discuss how decisions about which research to fund should be based on issues relevant to users of research. Next, John Ioannidis et al consider improvements in the appropriateness of research design, methods, and analysis. Rustam Al-Shahi Salman et al then turn to issues of efficient research regulation and management. Next, An-Wen Chan et al examine the role of fully accessible research information. Finally, Paul Glasziou et al discuss the importance of unbiased and usable research reports. These papers set out some of the most pressing issues, recommend how to increase value and reduce waste in biomedical research, and propose metrics for stakeholders to monitor the implementation of these recommendations.

How should medical science change?

Sabine Kleinert, Richard Horton

Biomedical research: increasing value, reducing waste

Malcolm R Macleod, Susan Michie, Ian Roberts, Ulrich Dirnagl, Iain Chalmers, John P A Ioannidis, Rustam Al-Shahi Salman, An-Wen Chan, Paul Glasziou

How to increase value and reduce waste when research priorities are set

Iain Chalmers, Michael B Bracken, Ben Djulbegovic, Silvio Garattini, Jonathan Grant, A Metin Gülmezoglu, David W Howells, John P A Ioannidis, Sandy Oliver

Increasing value and reducing waste in research design, conduct, and analysis

John P A Ioannidis, Sander Greenland, Mark A Hlatky, Muin J Khoury, Malcolm R Macleod, David Moher, Kenneth F Schulz, Robert Tibshirani

Increasing value and reducing waste in biomedical research regulation and management

Rustam Al-Shahi Salman, Elaine Beller, Jonathan Kagan, Elina Hemminki, Robert S Phillips, Julian Savulescu, Malcolm Macleod, Janet Wisely, Iain Chalmers

Increasing value and reducing waste: addressing inaccessible research

An-Wen Chan, Fujian Song, Andrew Vickers, Tom Jeff erson, Kay Dickersin, Peter C Gøtzsche, Harlan M Krumholz, Davina Ghersi,H Bart van der Worp

Reducing waste from incomplete or unusable reports of biomedical research

Paul Glasziou, Douglas G Altman, Patrick Bossuyt, Isabelle Boutron, Mike Clarke, Steven Julious, Susan Michie, David Moher, Elizabeth Wager

More information on the website of The Lancet

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